Next generation spatial genomics tools for the human brain
Active Project Grant Awarded Last action
- Award ID
- R44MH140731
- Recipient
-
Spatial Genomics, Inc. UEI C2CPGG8RZLV9
- Awarding agency
-
National Institute of Mental Health
National Institutes of Health, Department of Health and Human Services
- Obligated
- $2,488,152
Award facts
- Assistance listing
- 93.242 Mental Health Research Grants
- Completion date 72% complete
- Place of performance
- Pasadena, CA 91107, USA
Award details come from USAspending.gov.
Description
- Abstract
- Spatial genomics in human brain tissues has the ability to visualize gene expression programs in complex cell interactions that are involved in many neurological disorders. However, current spatial technology is often limited by the high autofluorescence in human brain samples and the poor RNA quality. At spatial genomics, we have commercialized the gene positioning system (GENEPS) platform that is based on the sequential fluorescence in situ hybridization (SEQFISH) technology (ENG ET AL, 2019) that allows 10,000 genes to be imaged directly in tissue samples. The major goal of this project is to develop next generation reagents to scale up the multiplexity of assays available on the GENEPS instrument. We will develop new assays that can be performed robustly across human brain tissues by the GENEPS platform.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $1,244,076 | |
| Original award | $1,244,076 |
Quick answers
Who received award R44MH140731?
R44MH140731 was awarded to Spatial Genomics, Inc. by National Institute of Mental Health (National Institutes of Health) on June 1, 2025.
How much is award R44MH140731 worth?
$2,488,152 has been obligated on R44MH140731.
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