Project Grant R44MH140129

Award Date 8/2/24
Completion Date 7/31/25
Dollars Obligated $300K
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
New York, NY 10023, USA
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  1. A multi-aperture (MA) imaging method featuring a concentric mirror system and stray-light collimator to significantly boost BLI sensitivity and enable multi-view imaging and 3D tomography.

  2. A body-conforming animal mold (BCAM) and organ probability map (OPM) to facilitate anatomical co-registration without complex hardware, enabling automated quantification across animal studies.

The modular InVivoScan platform is designed to offer a range of imaging capabilities, from high-throughput planar imaging to advanced 3D tomographic and multi-view imaging, in a compact and affordable solution. This research aims to overcome key limitations in current BLI technologies to advance preclinical imaging capabilities for applications in areas like cancer, infectious diseases, and pharmacokinetics. The award period runs from August 2024 to July 2025.

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