Automated enhancement and correction of brain MRI images that leverages the entire imaging exam

Ended Project Grant Awarded Last action

Award ID
R44MH135725
Recipient
Awarding agency
Obligated
$3,299,516

Award facts

Assistance listing
93.242 Mental Health Research Grants
Completion date
Originally
Place of performance
California, USA

Award details come from USAspending.gov.

Description

Abstract
Subtle medical, INC. (subtle), in collaboration with the university of washington, proposes a fast-track project to develop and validate a software product capable of enhancing an entire brain magnetic resonance imaging (MRI) study. The proposed system will use state-of-the-art machine learning methods to build a product that integrates seamlessly into the radiology workow and standard patient care path to determine if any required MRI acquisitions are missing or corrupted, then correct the corrupted acquisitions and synthesize the missing acquisitions by incorporating the information contained in the appropriately acquired acquisitions. Brain studies make up approximately 20% of all MRI studies worldwide, and nearly all brain studies acquire multiple image contrasts to obtain complementary information. IT has been reported that nearly 60% of all MRI acquisitions contain at least minimal motion artifacts. Moreover, important acquisitions are frequently skipped or forgotten during the study. The result is that a signicant fraction of brain MRI studies are sent to radiologists with missing or poor-quality exam sequences that can reduce the quality of care while increasing the burden on the radiologist to read a suboptimal study. A successful completion of this project will result in a tool for imaging centers that will improve the consistency and quality of brain MRI studies and allow them to increase their throughput by removing the need to rescan acquisitions with artifacts. This will improve the experience and care of the patients while reducing the burden on radiologists and improving the eiciency of the imaging center's operations.

Transactions

Action Obligated Date
Amendment -$0
Amendment -$203,594
Amendment -$203,594
Amendment $0
Amendment $0
Amendment $0
Amendment $1,135,581
Amendment $1,135,581
Amendment $1,135,581
Original award $299,961

Quick answers

Who received award R44MH135725?

R44MH135725 was awarded to Subtle Medical, Inc. by National Institute of Mental Health (National Institutes of Health) on September 5, 2023.

How much is award R44MH135725 worth?

$3,299,516 has been obligated on R44MH135725.

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