Multi-modal spatial genomics in the mouse and human brains

Ended Project Grant Awarded Last action

Award ID
R44MH133530
Recipient
Awarding agency
Obligated
$5,351,872

Award facts

Assistance listing
93.242 Mental Health Research Grants
Completion date
Originally
Place of performance
California, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
The major goal of this project is to build upon our existing expertise and platform to develop spatial multi-omics tools in human brains. At spatial genomics, we are commercializing the sequential fluorescence in situ hybridization (SEQFISH) technology (ENG ET AL, 2019) that allows thousands of genes to be imaged directly in brain samples. We have developed extensive experience working with mouse and human brains with our SEQFISH technology. Spatial genomics methods have the potential to identify novel cell types, reveal spatial organization of groups of cells and subcellular patterns, and elucidate signaling interactions between neighboring cells in the brain. Identifying the spatial organization of the human brain at cellular resolution from single cell gene expression profiles is essential to understanding neuronal circuits and interactions between neurons and glia.

Transactions

Action Obligated Date
Amendment $0
Amendment $0
Amendment $0
Amendment $1,337,968
Amendment $1,337,968
Amendment $1,337,968
Original award $1,337,968

Quick answers

Who received award R44MH133530?

R44MH133530 was awarded to Spatial Genomics, Inc. by National Institute of Mental Health (National Institutes of Health) on June 15, 2023.

How much is award R44MH133530 worth?

$5,351,872 has been obligated on R44MH133530.

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