Project Grant R44MH128484
- This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $256,627.00 to the University of Denver to develop and pilot test a digital intervention for parents of pre- and early adolescents. The goal is to support parents in responding effectively to suicide risk alerts generated by digital monitoring apps, thereby decreasing suicide-related behaviors in their children. The project involves three phases:...
- This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $661,237 over 5 years to The Ohio State University to conduct research on optimizing brief coping skills interventions for suicide prevention. The study aims to intensively characterize the contexts in which patients at high risk for suicide are most likely to use and benefit from their safety planning interventions, leveraging technology and...
- The National Institute of Mental Health (NIMH) awarded a $196,875 Project Grant (CFDA 93.242 - Mental Health Research Grants) to The Ohio State University to conduct research on "Digital Monitoring of Emotion Regulation and Suicidal Ideation Among Individuals at Clinical High Risk for Psychosis". The 2-year study aims to examine emotion regulation as a mechanism for suicidal ideation in individuals at clinical high risk for psychosis, using ecological momentary assessment, wearable...
- This Project Grant award of $178,319.00 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to the University of California, San Diego (UCSD) to develop and test a novel personalized suicide prevention intervention called PRECISE. The key objectives are to refine the PRECISE intervention using a user-centered design approach in Aim 1, then conduct a randomized controlled trial in Aim 2 to compare low-intensity versus...
- This federal Project Grant award of $740,250, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports the adaptation and evaluation of the Youth Nominated Support Team (YST) intervention to prevent the escalation of suicide risk among youth on probation. The project aims to address the high rates of suicide ideation and behaviors among justice-involved youth, who often face barriers to accessing needed mental health...
- This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $832,042 to Trustees of Dartmouth College to investigate the transmission of suicidal thoughts and behaviors among young adults on social media platforms. The multi-method research project aims to model suicide transmission as a real-time process and identify modifiable risk factors. It will employ computational social science, natural language...
- This Cooperative Agreement award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), will support a large-scale study to develop clinically actionable strategies for identifying individuals at risk of suicide. The $19,515,757 award to The Ohio State University will enable the recruitment of approximately 13,500 participants between the ages of 18 and 55, representing varying levels of suicide risk. The study will collect...
- This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is supporting the development and validation of an AI-enabled virtual assistant app called CLAIRITY. The app aims to automate the identification of individuals at risk of suicide, depression, and anxiety, and guide them to appropriate interventions. The $458,782 award will enable the awardee, Clarigent Corporation, to characterize the effects of using an...
- This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research to identify key engagement characteristics that can enhance the effectiveness of digital HIV interventions for at-risk youth. The $457,596 award to the University of Pennsylvania will fund a study that aims to: 1) harmonize engagement data from multiple Adolescent Medicine Trials Network for HIV Interventions (ATN) - UNC/Emory Center for...
- This federal Project Grant award, funded by the National Institute of Mental Health under the Mental Health Research Grants program (CFDA 93.242), supports a $792,006 research study on suicidality in autistic adults. The study aims to comprehensively examine the relationships between adversity, trauma, and protective factors in predicting suicidal ideation and behaviors in a sample of 250 autistic adults aged 18-40, with at least half being at high-risk for suicide. The longitudinal study...
DEVELOPMENT AND TESTING OF A DIGITALLY ASSISTED RISK REDUCTION PLATFORM FOR YOUTH AT HIGH RISK FOR SUICIDE - ABSTRACT DESPITE EFFORTS TO PREVENT SUICIDE, US RATES ARE CLIMBING, AND SUICIDE IS THE SECOND LEADING CAUSE OF DEATH AMONGST YOUTH. ALTHOUGH PROMISING APPROACHES ARE AVAILABLE FOR PREVENTATIVE INTERVENTIONS WITH YOUTH AT-RISK FOR SUICIDE, THEY DEMONSTRATE MODEST BENEFIT, AND RECENT REVIEWS HAVE CONCLUDED THAT NEW DEVELOPMENTS ARE REQUIRED THAT FACILITATE NOT ONLY GREATER EFFECTIVENESS, BUT ALSO ENHANCE TREATMENT ENGAGEMENT, ADHERENCE, AND CONTINUITY OF CARE AMONGST THESE YOUNG PEOPLE. DIGITAL TOOLS, ESPECIALLY PERSONAL SMARTPHONES, ARE PROMISING AVENUES TO ADDRESS THESE ISSUES AND CAN BE USED TO PROVIDE A UNIQUE UNDERSTANDING OF PROXIMAL RISK FACTORS, INCLUDING PSYCHOLOGICAL DISTRESS, ANHEDONIA AND BEHAVIORAL WITHDRAWAL, AND SLEEP DISTURBANCE AMONGST HIGH- RISK INDIVIDUALS. FURTHERMORE, DIGITAL METHODS CAN PROVIDE ONGOING SUPPORTIVE PATIENT CONTACT TO SUPPORT THE REDUCTION OF SUICIDE RISK. THE OVERALL AIM OF THIS FAST-TRACK SBIR PROPOSAL IS TO ENHANCE THE EFFECTIVENESS OF SELECTIVE AND INDICATED PREVENTION FOR YOUTH WHO ARE RECEIVED OUTPATIENT MENTAL HEALTH CARE BY DEVELOPING AND TESTING A COMPREHENSIVE DIGITAL PLATFORM THAT ALLOWS PRACTITIONERS TO INTEGRATE OBJECTIVE MOBILE SENSING AND HIPAA COMPLIANT CLIENT COMMUNICATION TOOLS INTO THEIR MANAGEMENT OF THESE YOUNG PEOPLE. WE HAVE DEVELOPED AN INITIAL MVP VERSION OF THESE PRODUCTS, AND IN PHASE I WILL UTILIZE USER-CENTERED DESIGN PRINCIPLES TO ENHANCE THE PRODUCT FIT WITH TYPICAL SERVICE DELIVERY SYSTEMS FOUND IN HEALTHCARE ORGANIZATIONS WORKING WITH HIGH-RISK INDIVIDUALS (I.E., INTENSIVE OUTPATIENT SERVICES). THE AIM OF PHASE II IS TO FURTHER OPTIMIZE THESE PRODUCTS AND CONDUCT A PRAGMATIC CLINICAL TRIAL OF THE EFFECTIVENESS, FEASIBILITY, AND ACCEPTABILITY OF THE PRODUCTS IN A REAL WORLD INTENSIVE OUTPATIENT CLINICAL SERVICE. WE WILL UTILIZE THE DATA GENERATED BY THIS TRIAL TO IMPROVE ADOPTION, IMPLEMENTATION FIDELITY, AND SUSTAINED USE OF THESE TOOLS, GUIDED BY AN IMPLEMENTATION SCIENCE FRAMEWORK.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $794.1k | 2/14/25 | ||
| Not listed | $0 | 11/15/24 | ||
| Not listed | $0 | 11/15/24 | ||
| Not listed | $50.0k | 5/14/24 | ||
| Not listed | $50.0k | 5/14/24 |