Project Grant R44MD017106
- Federal Project Grant Award Summary ISA Associates, Inc. received a $612,006 Project Grant award from the National Institute for Minority Health and Health Disparities (NIMHD) under the Minority Health and Health Disparities Research program (CFDA 93.307) to develop a mobile health intervention addressing preterm birth risk among African American women. The award, effective September 17, 2025, through July 31, 2026, supports the design and development of a culturally tailored,...
- Federal Project Grant Award Summary Boston College received a $440,217 Project Grant award from the National Institute on Minority Health and Health Disparities (NIMHD) under the Minority Health and Health Disparities Research program (CFDA 93.307), effective September 19, 2025, with a completion date of June 30, 2027. The award supports the development and evaluation of "Asking for Help" (A4H), a mobile health (mHealth) application designed to improve mental health outcomes for...
- This $2.14 million Project Grant, awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), funds a randomized controlled trial conducted by Duke University's Office of Research Administration. The award, obligated August 1, 2025, with completion by July 31, 2026, supports a multi-component lifestyle intervention study designed to improve cardiovascular and kidney health outcomes in Black adults with chronic kidney...
- This $1,410,766 Project Grant awarded by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to analyze the effectiveness of ongoing natural experiments in telehealth for managing uncontrolled blood pressure (BP) during the COVID-19 pandemic. The project will leverage the PCORnet Blood Pressure Control Laboratory to track the implementation of new BP-related technologies and strategies across healthcare systems. Through descriptive and causal inference...
- This federal Project Grant award of $708,678, provided by the National Heart, Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), aims to conduct a Sequential Multiple Assignment Randomized Trial (SMART) to reduce food insecurity and improve adherence in patients with hypertension. The key products and services to be delivered under this grant include: Determining the most effective initial food insecurity intervention (resource information or community health worker...
- Grant Award Summary KDH Research and Communication, Inc. received a $303,916 Project Grant award from the National Institute on Minority Health and Health Disparities under the Minority Health and Health Disparities Research program (CFDA 93.307), effective September 19, 2025 through September 18, 2026. The award funds development and evaluation of SUPPORT (Supplying Useful Perimenopause Through Post-Menopause Online Resources and Tools), a culturally appropriate training program designed to...
- This Project Grant award from the National Institute of Mental Health (NIMH), authorized under the Mental Health Research Grants program (CFDA 93.242), is for $692,070 to adapt and pilot test a digital health HIV prevention intervention for Black heterosexual couples in New York State. The primary objectives are to: 1) Adapt an existing digital health intervention to meet the specific needs of this target population; and 2) Conduct a 6-month pilot randomized controlled trial with 60 couples to...
- This $540,771 federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) will support research to develop a personalized, socially-aware stroke risk stratification tool for patients with atrial fibrillation (AF). The primary objectives are to: Discover new stroke risk factors for AF patients, incorporating social determinants of health (SDOH) data. An innovative Poisson Binomial Comorbidity (PBC) framework will be used to...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of Alabama at Birmingham a $1.47 million Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) on August 1, 2025, with completion scheduled for May 31, 2030. This randomized controlled clinical trial will evaluate the clinical implementation and efficacy of a systolic blood pressure (SBP) polygenic risk score (PRS)—a genetic assessment tool derived from over 1 million...
- MIRAME SALUD: Immersive Diabetes Self-Management Training for Latino Americans See Yourself Health LLC received a $771,632 Project Grant award from the National Institute on Minority Health and Health Disparities (NIMHD) under the Minority Health and Health Disparities Research program (CFDA 93.307), with an award date of April 29, 2025 and completion date of March 31, 2026. The project develops MIRAME SALUD, an avatar-driven immersive digital health platform designed to deliver culturally...
REDUCING HYPERTENSION AMONG AFRICAN AMERICAN MEN: A MOBILE STRESS MANAGEMENT INTERVENTION TO ADDRESS HEALTH DISPARITIES - PROJECT SUMMARY/ABSTRACT AFRICAN AMERICAN MEN HAVE THE HIGHEST RATE OF HYPERTENSION (HTN) IN THE UNITED STATES. ONCE DIAGNOSED, THEY ARE ALSO LESS LIKELY TO ACHIEVE BLOOD PRESSURE (BP) CONTROL. THIS HEALTH DISPARITY IS CRITICAL, AS ELEVATED BP IS THE PRIMARY MODIFIABLE RISK FACTOR FOR CARDIOVASCULAR DISEASE. ONE REASON FOR THIS HTN DISPARITY: STRESS. AFRICAN AMERICANS REPORT MORE STRESS THAN THEIR WHITE PEERS, MOST NOTABLY FROM RACIAL DISCRIMINATION, AND HAVE FEWER RESOURCES TO MANAGE THESE STRESSORS. AND THIS STRESS HAS SIGNIFICANT PHYSIOLOGICAL CONSEQUENCES. COMPARED TO WHITES, AFRICAN AMERICANS SHOW HEIGHTENED ALLOSTATIC LOAD, A BIOLOGIC MEASURE OF THE CUMULATIVE BURDEN OF CHRONIC STRESS THAT IS IMPLICATED IN THE ETIOLOGY OF HTN. STRESS ALSO EXACERBATES HTN THROUGH UNHEALTHY COPING (E.G., OVEREATING, ALCOHOL USE) AND POORER ADHERENCE TO ANTIHYPERTENSIVE MEDICATIONS. RESEARCH SHOWS THAT STRESS MANAGEMENT (SM) INTERVENTIONS IMPROVE HTN. DESPITE THIS, SM TRAINING IS NOT REGULARLY DEPLOYED TO MANAGE BP, OFTEN BECAUSE HEALTH CARE SETTINGS LACK THE RESOURCES TO DELIVER IT. ONE COST- EFFECTIVE, EASILY SCALABLE SOLUTION IS MOBILE PHONES (I.E., MHEALTH). IMPORTANTLY, 98% OF AFRICAN AMERICANS OWN A MOBILE PHONE. MOST ARE SMARTPHONES (83%). AND TEXT MESSAGING INTERVENTIONS HAVE BEEN SHOWN TO IMPROVE A VARIETY OF HTN MANAGEMENT LIFESTYLE CHANGES (E.G., SMOKING REDUCTION, PHYSICAL ACTIVITY ENHANCEMENT). THERE IS NO MOBILE COGNITIVE BEHAVIORAL SM INTERVENTION (M-CBSMI) ON THE MARKET TODAY THAT IS DESIGNED TO HELP AFRICAN AMERICAN MEN MANAGE RACIAL AND NONRACIAL SOURCES OF STRESS IN AN EFFORT TO REDUCE HTN DISPARITIES. THE PROPOSED INTERVENTION WILL FILL THIS VOID. USING PROVEN CBSMI TECHNIQUES, BLACK MEN WILL LEARN HOW TO MANAGE STRESS AND REDUCE BP THROUGH TEXT MESSAGES AND INTEGRATED VIDEOS. EDUCATIONAL TEXTS WILL INCREASE KNOWLEDGE, DEVELOP SKILLS, AND REDUCE BARRIERS TO ADAPTIVE COPING. SUPPORTIVE TEXTS WILL PROMOTE GENDER AND ETHNIC PRIDE. A LIBRARY OF INTERACTIVE VIDEOS WILL ALLOW A USER TO CHOOSE TAILORED TRAINING AND CONTENT BASED ON HIS PERSONAL NEEDS AND EXPERIENCES (E.G., UTILIZING A CHOOSE-YOUR-OWN-ADVENTURE STYLE). ALL VIDEOS WILL BE ACCESSIBLE THROUGH LINKS EMBEDDED WITHIN TEXT MESSAGES, MAKING IT EFFORTLESS TO VIEW THEM. IN PHASE I, A PROTOTYPE M-CBSMI WAS DEVELOPED. THIS DEVELOPMENT WAS INFORMED BY FORMATIVE RESEARCH WITH 20 AFRICAN AMERICAN MEN ACROSS THE LIFESPAN. THE RESULTS OF PHASE I STRONGLY SUPPORT THE FEASIBILITY AND POTENTIAL EFFECTIVENESS OF THE INTERVENTION, FAR EXCEEDING THE BENCHMARKS ESTABLISHED IN THE PHASE I PROPOSAL. DURING PHASE II, THE M-CBSMI FOR AFRICAN AMERICAN MEN WILL BE FULLY DEVELOPED. THEN, IN PARTNERSHIP WITH FAMILY AND MEDICAL COUNSELING SERVICE, THE EFFECTIVENESS OF THE M-CBSMI TO REDUCE BP AMONG HYPERTENSIVE AFRICAN AMERICAN MEN WILL BE EXAMINED. PARTICIPANTS WILL BE RANDOMLY ASSIGNED TO EITHER THE INTERVENTION CONDITION OR TO A MATCHED CONTROL CONDITION. SECONDARY MEASURES WILL ASSESS SUBJECTIVE STRESS, USE OF ANTIHYPERTENSIVE MEDICATIONS, COPING, WELL-BEING, GENDERED RACIAL IDENTITY, AND KNOWLEDGE.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 3/2/26 | ||
| Not listed | $0 | 8/15/25 | ||
| Not listed | $0 | 8/15/25 | ||
| Not listed | $0 | 5/5/25 | ||
| Not listed | $0 | 5/5/25 |