Project Grant R44HL154933

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $704,672 to Flowpoint Medical Inc. to develop an implantable self-sealing needle guide system to improve vascular access and safety for hemodialysis patients. The award will fund the refinement of the device's manufacturability and operational parameters, as well as a large animal...

This $2,252,419 Cooperative Agreement award, funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), supports the development of an innovative vascular conduit device for dialysis vascular access. The award brings together industry and academic partners to create the "Functional Integrated Electrospun (FINE)" device, which comprises an inner...

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $499,890 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to Pavaj Vascular Corporation to develop a novel therapy to prevent arteriovenous fistula (AVF) venous stenosis, a common complication in end-stage kidney disease patients requiring hemodialysis. The funding will support two main goals: 1) evaluating the stability and biocompatibility of a nanoparticle-based...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $298,371 to Anova Biomedical, Inc. to develop a new class of biodegradable and elastic vascular grafts for hemodialysis. The funding will be used to refine manufacturing techniques for these grafts, which are designed to closely resemble the mechanical properties of native vasculature and slowly remodel into...

This $518,661 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to advance the design of hemodialysis cartridges beyond the focus on urea removal. The project will test a novel parallel-plate dialyzer design that controls shear forces to potentially reduce platelet activation and clotting risks for the 548,000 Americans who rely on dialysis. The award to Vanderbilt...

This Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $274,811 to Anova Biomedical, Inc. to develop 3D printed personalized vascular grafts using novel elastomeric resins. The key objectives are to: 1) develop and characterize the novel 3D printing resin for producing personalized, elastic, and bioresorbable vascular grafts; 2) demonstrate the ability to 3D print vascular prosthetics using patient CT...

This NSF Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award to President and Fellows of Harvard College (Harvard University) provides $550,000 in funding from August 1, 2024 to July 31, 2026 to develop a minimally-invasive, catheter-based additive manufacturing platform capable of creating customized medical implants directly inside the human body. The project aims to transform the field of medical implants by enabling on-demand fabrication of personalized 3D-printed...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $312,088 to Sojourn Medtech LLC to develop the CANSIM simulator. The CANSIM is a smart, personalized, and dialysis-specific training device to teach critical cannulation skills to dialysis nurses and patient care technicians. The key features include: 1) dialysis-specific design, 2) realistic and low-maintenance...

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $350,000 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Katharos, Inc., a for-profit woman-owned business based in Denver, Colorado. The goal of this 1-year project is to develop and evaluate a novel extracorporeal device called the "PhosFilter" that can enhance phosphate removal from the blood of patients undergoing hemodialysis for...

This Project Grant award of $503,966 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) will support research to optimize and validate an AI model that screens for arteriovenous fistula (AVF) stenosis in dialysis patients using sound files from a digital stethoscope. The overarching goal is to determine if an AI-based screening approach leveraging...