Project Grant R44HL151147

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award for $997,142 aims to develop a rapid phenylalanine blood level monitor for patients with phenylketonuria (PKU), a lifelong genetic disorder. The product consists of a test strip and device that can provide frequent, accessible monitoring of phenylalanine levels from a finger prick to improve disease management and patient outcomes. The project focuses on optimizing the...

The National Heart, Lung, and Blood Institute (NHLBI) awarded a $297,587 Project Grant (CFDA 93.837 - Cardiovascular Diseases Research) to General Fluidics Corporation to validate the performance of the AXESS system, a novel point-of-need clinical chemistry and hematology platform. The goal is to demonstrate equivalence between the AXESS system's results and those obtained from standard venous blood testing for a basic metabolic panel and complete blood count, using matched capillary and...

Federal Grant Award Summary Award Overview: The National Heart, Lung, and Blood Institute (NHLBI) awarded Actiox LLC a $699,468 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) for development and validation of a wearable microneedle-based biosensor for continuous cardiac troponin I (cTnI) monitoring. The award was obligated on September 10, 2025, with a completion date of October 31, 2026, and will be performed at the company's La Jolla, California facility....

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $304,966 to Kompass Diagnostics Inc. aims to develop a portable, cost-effective diagnostic device that can rapidly detect multiple blood-based biomarkers. The key focus is on enabling rapid, quantitative measurement of reproductive hormones to support time-sensitive clinical decisions in fertility treatments. The research objectives include developing an integrated...

Levisonics Inc. was awarded a $998,857 cooperative agreement from the National Science Foundation under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) for the period of March 1, 2022 through February 29, 2024. The award will support the development of an innovative non-contact platform for low volume blood coagulation analysis using a single drop of blood. The technology aims to safely and reliably assess blood clotting in neonatal, pediatric, and vulnerable adult...

Ovid BP Systems Inc. received a $713,199 Project Grant award from the National Institutes of Health's National Heart, Lung and Blood Institute on April 15, 2021 to develop a blood pressure monitoring system using video recording on smart cameras. The goal of the Cardiovascular Diseases Research program, CFDA #93.837, is to support heart and vascular research. Under this award, Ovid BP will assess the feasibility of using video-based algorithms to accurately measure blood pressure through...

The National Heart, Lung, and Blood Institute (NHLBI) awarded a $295,153 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Safebeat RX Inc. The funding supports the development of a novel, smartwatch-enabled technology that allows patients with low-risk atrial fibrillation to safely initiate antiarrhythmic medications at home. The technology analyzes post-drug ECG data taken by patients using a machine learning algorithm and provides this information to...

This National Science Foundation (NSF) Cooperative Agreement award, under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, provides $999,553 to Dynocardia, Inc. to develop advanced computer vision and artificial intelligence algorithms for motion artifact correction in their Vitrack wearable blood pressure monitoring device. The project aims to improve the accuracy and reliability of Vitrack's continuous, non-invasive blood pressure measurements in clinical settings, where...

Dynocardia Inc. received a $256,000 National Science Foundation Project Grant to advance development of a novel continuous, cuffless blood pressure monitoring device. Funded through the NSF Engineering Directorate's SBIR program, the award will support Dynocardia's efforts to address motion artifacts and enable accurate, beat-to-beat blood pressure measurements in hospital intensive care and operating room settings. Accurate 24-hour blood pressure monitoring has potential to significantly...

Grant Award Summary Analytical Diagnostic Solutions Inc. received a $305,352 Project Grant award from the National Center for Advancing Translational Sciences (NCATS, CFDA 93.350) effective July 1, 2025, through June 30, 2026. The company is developing HCY NOW, a quantitative point-of-care device for home-based monitoring of total blood homocysteine (THCy) levels to improve management of homocystinurias (HCUs)—inherited metabolic disorders characterized by plasma homocysteine accumulation. The...