Synthoplate: intravenous hemostatic nanotechnology to mitigate bleeding in thrombocytopenia
Ended Project Grant Awarded Last action
- Award ID
- R44HL145948
- Recipient
-
Haima Therapeutics LLC UEI JKZPL4NA9V21
- Awarding agency
-
National Heart Lung and Blood Institute
National Institutes of Health, Department of Health and Human Services
- Obligated
- $8,285,089
Award facts
- Assistance listing
- 93.837 Cardiovascular Diseases Research
- Completion date
- Originally
- Place of performance
- Ohio, USA
Award details come from USAspending.gov.
Description
- Abstract
- The normal platelet count in human blood is 150,000-400,000/ΜL, and these platelets are responsible for efficient hemostatic surveillance and bleeding mitigation in the body. Thrombocytopenia (TCP, low platelet count) is a condition caused by a decrease in platelet production, increase in platelet destruction or consumption, or increase in splenic sequestration. The age-adjusted prevalence of immune thrombocytopenic purpura (ITP) is estimated to be 3.3 per 100,000 persons in the USA, while drug-induced TCP affects 1-2 per 100,000 persons. The majority (>95%) of TCP cases result from autoimmune disorders or are induced by chemo- and radiotherapies as well as other pharmaceuticals. At platelet counts
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | -$19,767 | |
| Amendment | $0 | |
| Amendment | $50,000 | |
| Amendment | $50,000 | |
| Amendment | $112,804 | |
| Amendment | $112,804 | |
| Amendment | $112,804 | |
| Amendment | $972,163 | |
| Amendment | $972,163 | |
| Amendment | $972,163 | |
| Amendment | $972,163 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $994,448 | |
| Amendment | $994,448 | |
| Amendment | $994,448 | |
| Original award | $994,448 |
Show all 18
Quick answers
Who received award R44HL145948?
R44HL145948 was awarded to Haima Therapeutics LLC by National Heart Lung and Blood Institute (National Institutes of Health) on June 1, 2019.
How much is award R44HL145948 worth?
$8,285,089 has been obligated on R44HL145948.
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