Project Grant R44HL144369

The National Heart, Lung, and Blood Institute (NHLBI) awarded a $295,153 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Safebeat RX Inc. The funding supports the development of a novel, smartwatch-enabled technology that allows patients with low-risk atrial fibrillation to safely initiate antiarrhythmic medications at home. The technology analyzes post-drug ECG data taken by patients using a machine learning algorithm and provides this information to...

This $275,000 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development and validation of an automated method for continuous post-operative cardiac rhythm diagnosis. The project, led by Atrility Medical, Inc., aims to improve the accuracy and accessibility of post-operative rhythm monitoring through the use of high-quality atrial electrogram signals. The anticipated outcome is a real-time, continuous...

Spheric Bio Inc. received a $598,636 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), dated September 25, 2025, with a completion date of September 14, 2026. The grant supports Phase I development of the EMULAATE platform, a minimally-invasive technology designed to create personalized, soft biomaterial implants for left atrial appendage (LAA) occlusion to prevent stroke in atrial fibrillation (AF)...

This $540,771 federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) will support research to develop a personalized, socially-aware stroke risk stratification tool for patients with atrial fibrillation (AF). The primary objectives are to: Discover new stroke risk factors for AF patients, incorporating social determinants of health (SDOH) data. An innovative Poisson Binomial Comorbidity (PBC) framework will be used to...

The University of South Florida received a $734K Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 19, 2025, through August 31, 2030. This research initiative investigates the relationship between atrial microvascular and endothelial dysfunction and the development of postoperative atrial fibrillation (POAF), a complication affecting 30-50% of cardiac surgery patients. The project...

This $1 million cooperative agreement from the National Science Foundation will support Reflodx, Inc. in developing a novel, noninvasive device to detect and characterize the presence or absence of a bolus in the upper esophagus. Under the NSF Technology, Innovation, and Partnerships program, Reflodx will continue work on a patented pulse-echo ultrasound technology using proprietary algorithms to create an acoustic signature that can differentiate a bolus in the esophagus. Over the two-year...

Federal Grant Award Summary Baylor College of Medicine received a $752,618 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 2, 2025, with completion targeted for May 31, 2030. The award supports comprehensive research investigating the role of inflammation in postoperative atrial fibrillation (POAF), a common complication of cardiothoracic surgery occurring in 10-50% of patients....

This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under CFDA 93.837 - Cardiovascular Diseases Research provides $570,537 to the University of California, Davis to investigate the role of calcium dysregulation in human atrial fibroblast behavior and its contribution to atrial fibrosis associated with atrial fibrillation (AF). The research aims to establish a mechanistic understanding of how calcium homeostasis in human atrial fibroblasts drives their...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant of $275,000 awarded to Xtract Medical Inc. aims to develop and demonstrate the feasibility of a novel catheter-based system for improved removal of blood clots during mechanical thrombectomy procedures to treat venous thromboembolism (VTE). The proposed system is designed to effectively remove large blood clots while minimizing damage to blood vessels and reducing complications such as...

Federal Grant Award Summary Baylor College of Medicine received a $673,598 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 15, 2025, through June 30, 2029. The award supports research investigating cardiomyocyte-fibroblast signaling mechanisms in atrial fibrillation (AF), a condition affecting an estimated 12 million Americans by 2030 and contributing to at least 175,000 deaths...