Project Grant R44HL108542

Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Children's Research Institute a $227,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective August 1, 2025 through July 31, 2027. This pre-clinical research project delivers investigative services focused on protecting thalamic neurons that regulate consciousness following cardiac arrest. The research employs...

Cooler Heads Care, Inc. was awarded a $632,981.28 Project Grant from the National Cancer Institute's Cancer Cause and Prevention Research program (CFDA 93.393) to develop a portable, patient-administered scalp cooling device and smartphone application. The goal is to reduce barriers to scalp cooling access for chemotherapy patients experiencing hair loss. Cooler Heads will develop training materials and conduct usability testing to demonstrate patients can self-administer the scalp cooling...

This federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $199,867 to the University of Washington to develop an innovative approach for long-term cryopreservation of organs using ice-free vitrification and single-mode electromagnetic resonance (SMER) heating. The project aims to overcome barriers in organ cryopreservation by advancing vitrification and EM heating technologies to enable fast and uniform rewarming of cryopreserved...

Federal Grant Award Summary Boston Children's Hospital received a $279,644 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 1, 2025, with completion scheduled for August 31, 2027. The grant funds research to develop and validate time to return of spontaneous circulation (ROSC) as a novel primary outcome measure for pediatric in-hospital cardiac arrest (P-IHCA) clinical trials. The research...

WINDSURFER Trial Cooperative Agreement Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a Cooperative Agreement valued at $1,535,439 to The Ohio State University on September 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct the WINDSURFER trial—a multi-site clinical study designed to determine the optimal non-invasive respiratory support (NIRS) strategy for treating acute hypoxemic respiratory failure in emergency departments. The trial...

Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a Project Grant of $180,936.00 to the University of Colorado-Denver under the Cardiovascular Diseases Research program (CFDA 93.837) effective July 24, 2025, with a completion date of June 30, 2030. This K23 award supports Dr. Fuchita's research initiative to build a sedation minimization culture in intensive care units (ICUs) by promoting evidence-based practices around the Spontaneous Awakening Trial...

Summary of Federal Project Grant Award Resuscitation Innovations LLC received $498,453 in funding from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) for the period of September 1, 2025 through August 31, 2026. The award supports the commercialization and refinement of the ELEGARD 3.0, a novel Head Up Position (HUP) CPR device designed to improve neurologically-intact survival rates for sudden cardiac arrest (SCA)...

This $437,461 federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), funded under the Cardiovascular Diseases Research program (CFDA 93.837), supports the development of a novel stabilization catheter device for His pacing lead implantation. The goal is to improve the accuracy and ease of His bundle pacing, an emerging alternative cardiac resynchronization therapy (CRT) for heart failure patients. The project aims to refine a deployable suction-tipped lead...

Federal Cooperative Agreement Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Medical University of South Carolina a $688,047 Cooperative Agreement on September 1, 2025, to conduct the WINDSURFER trial (WIN Ratio Analysis to Determine a Strategy of Non-Invasive Support for Respiratory Failure in the Emergency Department). This clinical research initiative will extend through August 31, 2031, and addresses a critical gap in emergency care by comparing the effectiveness...

This Project Grant, awarded May 7, 2026, by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), provides $473,860 in federal funding to The Regents of the University of Colorado-Denver through February 28, 2031. The award supports basic neuroscience research investigating heterosynaptic mechanisms that drive elevated synaptic inhibition and impaired synaptic plasticity...