Project Grant R44GM159519
- The National Institute of General Medical Sciences (NIGMS) awarded Fluorofinder, LLC a $356,190 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to advance a novel microscopy workflow tool. The tool is designed to streamline assay development, improve awareness and education around optimal selection of microscopy assay components (instruments and reagents), and enhance reproducibility in the field. The project aims to address common challenges in...
- This $1,977,264 federal Project Grant, awarded by the U.S. Department of Health and Human Services' National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop a novel multimodal imaging platform that combines fluorescence super-resolution and tomographic polarized light imaging. The project will create open-source computational imaging tools to recover the dielectric tensor in multiple scattering samples using...
- The National Institute of General Medical Sciences (NIGMS) awarded a $333,048 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Imagen Bioworks Inc. in Houston, TX. The goal of this 1-year project is to develop a versatile 2-photon microscopy platform, dubbed 2P-SPOTLIGHT, to isolate individual cells from 3D tissue samples and 3D cell cultures based on their spatial and temporal properties. This will enable researchers to conduct downstream multi-omics...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $330,076 to Trestle Optics LLC, a small disadvantaged business located in Irvine, California. The award supports the development of a novel photothermal microscopy platform integrated with spatial light interference imaging. This innovative instrument is designed to enable non-destructive profiling and mapping of...
- This federal Project Grant award of $349,280 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of advanced machine learning algorithms for ultra-high-density, ultra-high-precision single molecule localization microscopy (SMLM). The grant recipient, Xgenomes Corp., will create a SMLM video simulator to generate training data (Aim 1), build a machine learning-based grouping...
- The National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) awarded Panluminate Inc., a woman-owned small business in Connecticut, a $404,117 project grant on June 15, 2025. The purpose of the grant is to develop CHROMEX30, a novel variant of Panluminate's proprietary Pan-Expansion Microscopy (PAN-EXM) technology, to enable high-resolution (~10 nm) nanoscale imaging of genetic organization and disease phenotypes. The key project goals are to: (1) develop, optimize, and...
- This $306,788 federal Project Grant was awarded on September 30, 2025 by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports the development of advanced probe technologies for ultrasensitive, quantitative RNA imaging using Hybridization Chain Reaction (HCR) amplification methods. The research aims to enable multiplexed, high-resolution imaging of gene expression patterns in highly autofluorescent...
- The National Institute of General Medical Sciences (NIGMS) awarded a $290,536 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to Trestle Optics LLC, a small disadvantaged business, to develop a novel high numerical aperture catadioptric lens for ultra-broadband multimodal microscopy. This lens will enable advancements in existing nonlinear optical imaging modalities, such as three-photon excited fluorescence and third-harmonic generation, by overcoming limitations of...
- This $417,400 federal Project Grant was awarded on April 10, 2025 by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to the Battelle Memorial Institute's Pacific Northwest National Laboratory. The grant supports the development and advancement of mass spectrometry imaging (MSI) tools to enable more accurate and comprehensive chemical characterization of the glycome (the complete repertoire of cell carbohydrates)...
- This Project Grant award, valued at $1,963,850.00 and awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of a novel "Differentiable Microscopy" technology at the Massachusetts Institute of Technology (MIT). The project aims to create a high-throughput, end-to-end imaging cytometry system by leveraging customizable nano-optics and machine learning techniques. The goal...
This $1,416,590 federal Project Grant was awarded on August 6, 2025 by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant recipient is Panluminate Inc., a woman-owned small business in New Haven, Connecticut specializing in advanced microscopy and spatial biology technologies. The key products and services to be delivered through this funding are: This project aims to significantly advance Panluminate's spatial biology research and development, with the goal of commercializing the Pan-XLSM platform as a standalone product in the future.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.4m | 8/6/25 |