Dialysate regeneration based on photo-electrochemical urea oxidation and reactive adsorption systems

Active Project Grant Awarded Last action

Award ID
R44DK137677
Recipient
Awarding agency
Obligated
$853,604

Award facts

Completion date 83% complete
Place of performance
Seattle, WA 98109, USA

Award details come from USAspending.gov.

Description

Abstract
In phase I of this program (STTR), we demonstrated that we could engineer our patented dialysis system enabling blood cleansing with just 2 liters of H20 (dialysate solution) to fit into a rollaboard-sized suitcase. This reduction in form factor is a critical element in commercializing a portable dialysis system to improve patient outcomes via longer dialysis sessions and also improve patient satisfaction/acceptance, freeing them from three visits per week to dialysis centers. The portable dialysis system eliminates urea via a TIO2 photo- activated catalyst that decomposes the urea to CO2 and N2 with 99% efficiency. Our present manufacturing method for the TIO2 catalyst involves a high temperature, high pressure hydrothermal autoclave. Though IT produces acceptable catalytic activity, reproducibility is poor and due to the extreme conditions in the autoclave, IT will be difficult, maybe impossible, to scale-up and commercialize. We seek funding to develop an ionized gas plasma-based production system for TIO2 catalyst production. Preliminary trials demonstrate that we can produce high activity TIO2 catalyst surfaces in reasonable time periods. This sbir application focused on the commercialization of our kidney dialysis system, will (1) scale up the plasma production of the TIO2 catalyst, (2) explore chemical doping using carbon, nitrogen, fluorine, phosphorous, silver, gold and platinum, and (3) demonstrate that our new catalyst surfaces are durable, have good catalytic activity and do not produce undesirable side-products.

Transactions

Action Obligated Date
Amendment $0
Original award $853,604

Quick answers

Who received award R44DK137677?

R44DK137677 was awarded to Kuleana Technology, Inc. by National Institute of Diabetes and Digestive and Kidney Diseases (National Institutes of Health) on September 22, 2023.

How much is award R44DK137677 worth?

$853,604 has been obligated on R44DK137677.

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