The National Science Foundation Division of Industrial Innovation awarded Spinex Inc. a $255,568 Project Grant under the Engineering (47.041) federal grant program. The grant funded the development of a transcutaneous electrical spinal cord neuromodulator for home use from September 1, 2021 to February 28, 2022. As part of its mission to foster innovation and excellence in engineering, the Engineering program supported Spinex Inc.'s work to advance technologies for non-invasive spinal cord...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,976 to Ecate LLC aims to develop a novel intraspinal stimulator system to restore sensation and volitional motor control in spinal cord injury patients. The project will fabricate nanopatterned stimulating electrodes coupled with custom CMOS chips to deliver spatially selective electrical stimulation to the spinal cord. This closed-loop neural interface system is intended...
This $183,397 project grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, aims to optimize epidural stimulation techniques for reducing spasticity in individuals with spinal cord injury (SCI). The key research objectives are to: 1) determine an optimal electrode configuration for epidural stimulation to decrease spasticity and hyperreflexia...
This $586,525 federal Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is funding the development of a non-invasive infrared light therapy and medical device to treat acute spinal cord injury (SCI). The primary awardee, Wayne State University, is leading this research effort to reduce reactive oxygen species production and restore...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will provide $690,638.00 to The University of Texas Health Science Center at San Antonio (UTHSCSA) over a 4-year period from September 2024 to May 2028. The funding will support a Phase 4, double-blind, randomized, and placebo-controlled study to investigate the glycemic and weight loss effects of...
This federal Project Grant award in the amount of $625,060 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will fund research to elucidate the specific roles of distinct spinal cord cell types in mediating interstitial cystitis (IC)/bladder pain syndrome (BPS). The study will use chemogenetic and optogenetic approaches to determine how...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $238,500 to the University of Pittsburgh to evaluate the use of spinal cord stimulation (SCS) to regain bladder function following spinal cord injury (SCI). The research aims to achieve two key objectives: 1) Evaluate the ability of SCS to evoke both micturition and continence...
This $151,559 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program aims to develop innovative magnetically responsive drug delivery electrospun fibers to improve regeneration after spinal cord injury (SCI). The key products and services to be delivered include: Fabrication of magnetic, growth factor-loaded coaxial electrospun fibers...
This Cooperative Agreement award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,594,319 to develop an innovative, non-invasive device called Breathing-Controlled Electrical Stimulation (BREESTIM) for the management of neuropathic pain after spinal cord injury. The award aims to: 1) Develop an integrated BREESTIM device under FDA quality systems, 2) Conduct a single-center randomized...
Teliatry Inc. received a $768,138 project grant award from the National Institutes of Health's National Institute of Biomedical Imaging and Bioengineering to develop a minimally invasive, single incision, rechargeable spinal cord stimulation system for chronic pain management. The grant was awarded under the Discovery and Applied Research for Technological Innovations to Improve Human Health program. Through this award, Teliatry will engineer the world's smallest (0.75cc), most cost-effective...
The Spinex Inc. was awarded a $4,719,091 Project Grant from the National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases to develop and clinically validate a transcutaneous electrical spinal cord neuromodulation (TESCON) device to mitigate symptoms of neurogenic bladder resulting from spinal cord injury. The award, made under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support Spinex in building a commercial version of their TESCON prototype, and conducting a multicenter randomized controlled trial to evaluate the device's effects on managing lower urinary tract function in individuals with spinal cord injuries. Specifically, the trial aims to demonstrate TESCON's ability to improve bladder capacity, diminish urinary incontinence, and restore bladder sensation. Successful completion of this clinical study will provide evidence to support a 510(k) submission to the FDA. The two-year project period began August 15, 2021.