Ramona Optics Inc., a self-certified small disadvantaged business, received a $400,000 Project Grant from the National Cancer Institute under the federal Cancer Detection and Diagnosis Research program (CFDA 93.394) to develop a new parallelized computational microscope platform called the MCAM-96. This platform aims to enable 50x faster 3D imaging of tumor organoids and live-cell assays compared to current microscopy systems. The MCAM-96 hardware and software will allow simultaneous imaging of 96 samples with high-resolution 3D and fluorescence capabilities, as well as rapid data processing and analysis. Ramona Optics will partner with research labs at Virginia Tech and Wake Forest University to benchmark the MCAM-96 system in experiments measuring the cytotoxic effects of chemotherapy on liver organoids and tracking the impact of immunotherapy on tumor organoids. This grant award supports Ramona Optics' ongoing efforts to develop innovative microscopy technologies that can accelerate biological research, particularly in areas like cancer biology and drug discovery.
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