Sonodynamic therapy using MRI-guided focused ultrasound in combination with 5-aminolevulinic acid to treat recurrent glioblastoma multiforme

Active Project Grant Awarded Last action

Award ID
R44CA275508
Recipient
Awarding agency
Obligated
$2,185,843

Award facts

Assistance listing
93.394 Cancer Detection and Diagnosis Research
Completion date 80% complete
Originally
Place of performance
Berkeley, CA 94710, USA

Award details come from USAspending.gov.

Description

Abstract
Glioblastoma multiforme (GBM) is a rare and deadly cancer. First line treatment for GBM includes maximal surgical resection with radiotherapy administered post-surgery, and concomitant administration of adjuvant temozolomide. Tumor recurrence is nearly inevitable due to the microscopic, infiltrating cells that are found centimeters from the margin of visible tumor mass. There is currently no effective standard of care for recurrent (rgbm) and this highly aggressive disease leads to death within 15 months after diagnosis and has a 5-year survival rate of

Transactions

Action Obligated Date
Amendment $796,215
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $694,814
Original award $694,814

Quick answers

Who received award R44CA275508?

R44CA275508 was awarded to Sonalasense, Inc. by National Cancer Institute (National Institutes of Health) on April 1, 2023.

How much is award R44CA275508 worth?

$2,185,843 has been obligated on R44CA275508.

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