Project Grant R44AI197309
- Federal Grant Award Summary Cellia Science, Inc. received a $306,872 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 5, 2025, through August 31, 2027. The company is developing a point-of-care diagnostic tool for Spontaneous Bacterial Peritonitis (SBP), a serious infectious complication affecting 10-30% of hospitalized cirrhosis patients with mortality rates of...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Massachusetts Institute of Technology $424,265 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 7, 2025, for a project period extending through July 31, 2027. The project develops an integrated Density-shift Immunocapture Separation-Raman (DIMS-RAMAN) platform designed to rapidly isolate and analyze bacterial pathogens from blood samples within approximately 1-2...
- Federal Grant Award Summary Partillion Bioscience Corp received a $306,865 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), with an award date of July 16, 2026 and completion date of June 30, 2027. The project focuses on advancing monoclonal antibody (mAb) discovery through enhanced development and commercialization of the company's proprietary nanovial technology—a hydrogel...
- Federal Grant Award Summary Scanogen Inc., a minority-owned small business, received a $969,449 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on September 17, 2025. The award supports a Commercialization Readiness Pilot (CRP) program focused on scaling and regulatory advancement of the company's Single Molecule Tethering (SMOLT)-based yeast detection platform. The platform delivers...
- Federal Project Grant Award Summary Protabit LLC received $304,602 in Project Grant funding from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award, effective August 7, 2025, with completion targeted for July 31, 2026, supports the development of high-throughput engineering technologies for bispecific antibodies—therapeutic molecules that combine two different antigen-binding domains. The project...
- Federal Project Grant Award Summary L2 Diagnostics LLC received a $293,142 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 21, 2025, with completion targeted for August 31, 2027. The grant supports development of a rapid diagnostic test (RDT) in lateral flow assay (LFA) format for detecting Babesia microti infection. The test targets BMGPI12 (BMSA1), a secreted protein...
- Federal Grant Award Summary Biotherapeutics, Inc. received a $628,726 SBIR Phase 1 Project Grant awarded on August 13, 2025, by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports the development of a novel, host-targeted, antibiotic-sparing oral therapeutic for the concurrent treatment of Clostridioides difficile infection (CDI) and inflammatory bowel disease (IBD). The innovative...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, College Park $1.795 million under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a four-year project period (August 1, 2025 – July 31, 2029). The award supports development of a Phenotypically Amplified Beta-Lactamase (PHABL) assay, a rapid diagnostic tool designed to identify beta-lactam-resistant bacterial pathogens in bloodstream...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Applied Biomedical Science Institute a Project Grant of $976,318 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 6, 2026, with completion targeted for March 31, 2031. The award funds research to elucidate the molecular mechanisms underlying ultralong complementarity-determining region H3 (CDR H3) antibodies produced by cattle. The Institute will...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award supports the development of a novel device that can rapidly and automatically extract pathogen DNA from whole blood samples to enable faster diagnosis of sepsis. The $274,858 award to New England Hemolytics, Inc., with a project period from September 1, 2024 to February 28, 2025, will fund the testing and optimization of this technology across common sepsis-causing pathogens. The...
Helixbind, Inc. received a $1,029,859 Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 16, 2026, with completion expected June 30, 2029. The award supports development of an automated, sample-to-answer molecular diagnostic system for rapid characterization of bloodstream infections directly from whole blood. The platform leverages proprietary technologies in sample preparation and detection to identify viable pathogens and antimicrobial resistance (AMR) genes within approximately four hours—significantly faster than traditional blood culture methods that require days for results. The assay menu encompasses organisms responsible for 98 percent of bloodstream infections and demonstrates single colony-forming unit per milliliter sensitivity without requiring centrifugation or filtration preprocessing. Under this funding, Helixbind will advance the platform to a hospital-ready alpha version by incorporating enhanced capabilities into a breadboard, bench-top instrument that operates with disposable plastic consumables. The diagnostic system addresses a critical clinical need: septicemia contributes to over 270,000 annual U.S. deaths, and rapid, accurate pathogen identification is essential for timely administration of appropriate antimicrobial treatment to improve patient outcomes and reduce hospitalization duration. This development effort supports the commercialization pathway for an innovative diagnostic tool that overcomes limitations of culture-dependent methods, particularly in patients already receiving antimicrobials.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 7/16/26 |