Project Grant R44AI096551

The National Science Foundation (NSF) awarded a $550,000 Project Grant under the NSF Technology, Innovation, and Partnerships (TIP) program to the University of California, Los Angeles (UCLA) to develop a rapid, multiplexed diagnostic tool for serological testing of tick-borne diseases (TBDs). This 2-year project seeks to improve blood-based detection of TBDs, including Lyme disease, Babesia, Anaplasma, and relapsing fever, through an innovative point-of-care (POC) serological assay. The goal is...

This federal Project Grant award of $1,176,645.00, granted by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports the development of a highly accurate proteomic diagnostic assay to identify active Borreliosis (Lyme disease) infection with point-of-need collection technology. The grant recipient, George Mason University, will conduct this research in collaboration with a subcontract to The Johns Hopkins University, which will provide...

Federal Project Grant Award Summary L2 Diagnostics LLC received a $293,142 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 21, 2025, with completion targeted for August 31, 2027. The grant supports development of a rapid diagnostic test (RDT) in lateral flow assay (LFA) format for detecting Babesia microti infection. The test targets BMGPI12 (BMSA1), a secreted protein...

Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Leland Stanford Junior University a $436,236 Project Grant effective August 1, 2025, through July 31, 2027, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports development of a novel epitaxial graphene-based biosensor to enable rapid and sensitive detection of active Borrelia burgdorferi (Bb) infections, the causative agent of Lyme disease....

The Department of Defense's Defense Health Agency awarded a $1,330,054 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to the Regents of the University of California, San Francisco (UCSF). The grant supports the "CLINICAL VALIDATION AND IMPLEMENTATION OF A HOST-PATHOGEN-BASED DIAGNOSTIC ASSAY FOR EARLY LYME DISEASE AND OTHER TICK-BORNE INFECTIONS" project, with a performance period from July 1, 2024 to June 30, 2027. As a leading academic medical...

This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to RT Microdx Inc. provides $274,362 to develop a novel molecular diagnostic platform for detecting respiratory diseases like strep throat. The platform aims to provide laboratory-quality accuracy for at-home use by non-healthcare professionals. Key technical objectives include optimizing the sensitivity of the platform's pH-sensitive polymer detection mechanism and ensuring robust performance at...

Federal Cooperative Agreement Summary Prompt Diagnostics, Inc. received a $1.25M Cooperative Agreement from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), awarded June 15, 2025, with completion targeted for May 31, 2027. The company is developing an automated, multiplexed point-of-care diagnostic platform for rapid detection and quantification of Treponema pallidum infections (syphilis). The solution integrates magnetic...

Federal Project Grant Award Summary Luna Bioscience, Inc., a woman-owned small business based in Westport, Connecticut, received a $600,870 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) awarded on September 24, 2025, with completion targeted for August 31, 2027. The grant supports the development of solid-phase antibody-detection assays for the diagnosis of acute leptospirosis, a...

Federal Project Grant Award Summary The University of Connecticut Health Center received a $457,875 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025, through June 30, 2027. The award supports biomedical research investigating the role of the RpoS (sigma factor) regulatory protein in the persistence of Borrelia burgdorferi, the spirochete bacterium that causes...

Controlpoint Inc. was awarded a $256,000 Project Grant from the National Science Foundation to develop a rapid, single-use, point-of-care lateral flow device for detecting kennel cough pathogens. The one-year award, made under the NSF Technology, Innovation, and Partnerships program, will support test validation, prototype manufacturing, and clinical evaluation to demonstrate the feasibility of detecting multiple bacteria and viruses associated with kennel cough in a single diagnostic test....