Project Grant R44AG097349
- This $499,588 Project Grant was awarded on September 22, 2025 by the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866) to Exqor Technologies Inc., a small disadvantaged business located in Boston, MA. The goal of this project is to develop non-radioactive nanoprobes that can be used for magnetic resonance imaging (MRI) of the tropomyosin receptor kinase B (TrkB) protein, which is implicated in the pathology of Alzheimer's disease (AD). The...
- The U.S. National Institute of Mental Health (NIMH) awarded a $380,375 Project Grant (CFDA 93.242 - Mental Health Research Grants) to Ceretype Neuromedicine Inc. to develop an advanced functional MRI software platform as a medical device for clinical trials and therapeutic applications in neuropsychiatry. The goal is to create a standardized, high-performance fMRI solution to support the development of new treatments for neuropsychiatric disorders by providing objective biological evidence of...
- This SBIR Phase I federal grant award, funded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, is supporting the development of a low-cost, AI/machine learning-based diagnostic tool for detecting Alzheimer's disease (AD) and mild cognitive impairment (MCI) using MRI brain scans. The $303,089 project, awarded to Bioimaginix LLC, a small business located in Morgantown, WV, aims to create an image analysis platform that can...
- The National Science Foundation (NSF) awarded a $1,186,778 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Adialante L.L.C. This Small Business Innovation Research (SBIR) Phase II project focused on the commercialization of a novel Magnetic Resonance Imaging (MRI) platform. The new MRI system provides silent, high-quality brain imaging at just one-tenth the cost and footprint of traditional MRI scanners, enabled by a breakthrough "B1...
- This $1,336,000 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the CFDA 93.286 "Discovery and Applied Research for Technological Innovations to Improve Human Health" program supports the development of a rapid, motion-robust, and low-gadolinium MRI technology for pediatric brain tumors. The key objectives are to (1) develop cutting-edge technologies for rapid, motion-robust, and quantitative MRI scans to reduce sedation needs...
- This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I grant award of $275,000 to Adialante L.L.C. focuses on the development of techniques to facilitate the design and fabrication of affordable, compact, and patient-friendly magnetic resonance imaging (MRI) systems, particularly for pediatric applications. The project aims to innovate novel B1 imaging approaches, such as Frequency-Encoded and Phase-Encoded Frequency-Modulated Rabi-Encoded Echoes (FREE), that...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,161,839 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to the University of Wisconsin-Madison, to be completed by May 31, 2029. The project aims to develop technologies that improve the value, efficiency, accessibility, and user experience of magnetic resonance imaging (MRI). Key objectives include increasing scanning speed,...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $927,318 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286) to the Regents of the University of Michigan. The goal of this 4-year project is to develop a "silent, whole-brain functional MRI (fMRI) acquisition" that can be used for cognitive neuroscience research and clinical applications, overcoming limitations...
- This federal Project Grant award, valued at $514,357.00, was provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286). The award supports the development of a portable, liquid-helium-free 1-T/560-mm RT bore point-of-care MRI magnet prototype at the Massachusetts Institute of Technology (MIT). This innovative technology aims to transform the...
- This $4.46 million project grant from the National Institute on Aging, part of the Department of Health and Human Services, supports research under the Aging Research program (CFDA 93.866) to develop a new in vivo magnetic resonance imaging biomarker for early detection of Alzheimer's disease neurodegeneration. Specifically, the awardee, Washington University, will utilize quantitative gradient recalled echo MRI techniques to identify two types of hippocampal tissue in preclinical and mild...
This SBIR Fast Track Project Grant, funded by the National Institute on Aging (CFDA 93.866 - Aging Research), aims to develop a "Universal FIRMM" system to provide real-time monitoring and reduction of patient motion during MRI scans. The $699,964 award to Turing Medical Technologies Inc. (doing business as Nous Imaging, Inc.) will deliver proof-of-concept (Phase I) and build a clinical-ready version (Phase II) of this motion-tracking technology. The objective is to address the significant problem of patient motion disrupting MRI scans, which is particularly challenging for the growing number of MRI scans required to monitor Alzheimer's disease drug treatments and related brain imaging abnormalities. The proposed Universal FIRMM system aims to be compatible with all MRI pulse sequences and require no modifications to clinical workflows, providing scan operators and physicians with real-time motion data to improve scan quality.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $700.0k | 9/19/25 |