Project Grant R44AG091101
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $320,511 project grant to TRU Diagnostics Inc. to develop a novel diagnostic tool for chronic diseases. The project aims to create a "non-stochastic W function epigenomic roadmap" using systems-based dynamic modeling to capture the shifting homeostatic set points of epigenetic markers over time. This transformative approach aims to enable personalized, dynamic health forecasts...
- The National Institute on Aging (NIA) awarded a $397,902 Project Grant to Panluminate Inc., a woman-owned small business in Connecticut, to develop FLASH-PULSE, an automated and multiplexed imaging solution for rapidly mapping the distribution of specific cell markers within tissue samples at the subcellular scale. The project aims to create a microfluidics-based system and novel probes to enable 32-plex protein imaging of formalin-fixed paraffin-embedded (FFPE) tissue samples without the need...
- This federal Project Grant award of $291,913 was provided by the National Institute on Aging (CFDA 93.866 - Aging Research) to Virscio, Inc., a for-profit research company located in Connecticut. The award is focused on developing epigenetic and senescent biomarkers using non-human primate tissues to advance the understanding of biological aging processes and potential anti-aging strategies. The project aims to create minimally invasive biomarker tools, such as blood and skin-based assays,...
- This $500,000 Project Grant awarded by the National Institute on Aging (CFDA 93.866 Aging Research) will support Sxrna Technologies, Inc. in developing an organoid toolkit for Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD). The company aims to create a platform for identifying senescent cells in living tissue, which can provide insights into the aging process and enable high-throughput drug screening in complex 3D tissue models. Specifically, the grant will fund...
- This $500,000 Project Grant was awarded on September 15, 2024 by the National Institute on Aging (CFDA 93.866 Aging Research program) to Neucyte Inc., a minority-owned small business specializing in advanced biomedical research and development. The funding will support the development of a miniaturized "mini-brain" microphysiological system (MPS) platform using Alzheimer's disease (AD) patient-derived cells. The goal is to create a scalable, reproducible in vitro brain model that can...
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded Adeptrix Corp. a $499,940 Project Grant on Sep 11, 2025 to develop TAUTRACE, an ultrasensitive immunoassay platform for quantifying distinct molecular forms of the tau protein in cerebrospinal fluid and plasma at femtogram/milliliter levels. This innovative technology enables the detection of single ions, allowing for the quantification of tau proteoforms as critical Alzheimer's disease...
- This federal Project Grant award for $1,249,147.00 was provided by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866). The grant is a collaborative effort between Epicypher, Inc., a biotechnology company in Durham, North Carolina, and Dr. Nicolas Young of Baylor College of Medicine to develop a novel platform called AgingPTM for studying aging-associated combinatorial histone post-translational modifications (ACPTMs) in tissue. This platform is intended to...
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $426,555 project grant to Duke University to develop a novel molecular diagnostic technology called "Cascade Amplification by Recycling Trigger Probe" (CARTP) for rapid, multiplex, and ultra-sensitive detection of circulating microRNA (miRNA) biomarkers in clinical plasma samples for the early detection of Alzheimer's disease (AD). The project aims to address the technical...
- The U.S. National Institute on Aging (NIA) awarded a $1,089,329 Project Grant to Homecare Hub US Inc. under the Aging Research Federal Grant Program (CFDA 93.866) to scale a network of small community-based care homes as a high-value alternative to institutional long-term care. The project aims to demonstrate improved health outcomes for seniors by leveraging a technology platform that facilitates personalized, cost-effective care through a decentralized network of 2-12 person residential care...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $1,249,957 Project Grant under CFDA 93.866 (Aging Research) to Advantage Therapeutics, Inc. in Florida. The grant aims to perform IND-enabling studies on a small molecule that is disease-modifying, low-cost, and has a long safety record for the treatment of Alzheimer's disease. The proposed molecule is designed to reduce brain inflammation and restore phagocytosis, thereby improving the...
The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $306,871 Project Grant to Fluid Discovery, Inc. under the Aging Research Federal Grant Program (CFDA 93.866). The grant supports the translation and commercial development of FIND-SEQ, a novel cell sorting technology that enables the isolation and profiling of rare cells in primary human tissues, even without known surface markers. This fast-track Small Business Innovation Research (SBIR) project aims to develop FIND-SEQ into a first-generation commercial product and validate its use for neurodegenerative disease research, a key application area. Successful completion of this project is crucial for Fluid Discovery to commercialize FIND-SEQ and meet the growing market demand for advanced rare cell isolation and sequencing technologies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $306.9k | 9/12/25 |