Project Grant R44AG090247
Award Date
9/20/24
Completion Date
8/31/25
Dollars Obligated
$799K
Federal Agency
National Institute on Aging
Federal Grant Program
93.866
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $299,893 to Pascall Systems, Inc. to develop a novel system that combines pre-operative cognitive assessment with Pascall's FDA-cleared wireless EEG technology for intraoperative monitoring. The goal is to enable personalized anesthesia care and effective monitoring of postoperative neurocognitive disorders (PNDs) in elderly surgical patients. The key products and services to be delivered...
This Project Grant award from the National Institute on Aging (NIA) under CFDA 93.866 - Aging Research, totaling $3,491,602.00, supports the development of an integrated brain state monitoring system for personalized anesthesia decision support to prevent post-operative delirium in elderly patients and those at risk for Alzheimer's or related dementias. The key products and services to be delivered include: 1) establishing technical feasibility in connecting the monitoring system with electronic...
This Project Grant award of $835,056, provided by the National Institute on Aging (CFDA 93.866 Aging Research), supports the development of a multi-modal system of wearable biosensors and predictive analytics to enable continuous monitoring of mobility and cognitive function in older adults. The primary goals are to: Develop a system of flexible, breathable, and inconspicuous eutectogel sensor patches that can provide real-time monitoring of biophysical domains like gait, posture, heart rate,...
The National Institute on Aging (NIA) awarded a $780,466 Project Grant (CFDA 93.866 Aging Research) to The Regents of the University of Colorado, doing business as the University of Colorado-Denver, with a period of performance from December 15, 2024 to November 30, 2029. The goal of this project is to develop digital biomarkers using single-channel sleep electroencephalography (EEG) to monitor brain health and detect pathological aging and early neurodegenerative changes, such as those seen...
This Project Grant award from the National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), is supporting research to investigate the role of interleukin-6 (IL-6) trans-signaling in the development of postoperative cognitive decline in aging and Alzheimer's disease. The total award amount is $3,284,161 over the project period from September 15, 2024 to May 31, 2029. The research will be conducted by The Regents of the University of California, San Francisco to address...
This $2,356,117 federal Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) will support research to improve the perioperative management of patients with Alzheimer's disease and related dementias. The primary objectives are to: (1) identify the extent to which surgical patients with these conditions are at increased risk for adverse postoperative outcomes, and (2) estimate the association between various perioperative interventions and the incidence...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to develop effective, scalable tools and interventions to reduce postoperative mortality, delirium, cognitive decline, and other adverse outcomes in vulnerable elderly surgical patients. The 5-year, $801,268 award to the University of Pittsburgh will fund research to create reliable preoperative risk prediction models and enable proactive multimodal perioperative interventions, including...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $1,498,158 to Synaptic Health LLC to develop a novel closed-loop feedback neuromodulation system to improve slow wave sleep in Alzheimer's disease patients. The goal of this Phase I project is to create a testable prototype that can sense sleep architecture and provide peripheral neuromodulation stimulation to individuals over 65, a high-risk group for Alzheimer's disease. Successful...
The U.S. National Institute on Aging (NIA) awarded a $134,000 project grant under the Aging Research program (CFDA 93.866) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct a pilot study on a digital cognitive behavioral therapy for insomnia (DCBT-I) intervention for older adults undergoing orthopedic surgery. The goal is to evaluate the feasibility and efficacy of this abbreviated DCBT-I protocol in improving sleep and cognitive resilience...
The National Institute on Aging (NIA), under the Federal Aging Research program (CFDA 93.866), awarded a $245,148 project grant to Eyenexo LLC to develop an automated rodent behavior testing system for non-invasively assessing early-stage Alzheimer's disease (AD). The project aims to develop a behavior biomarker that can differentiate AD from normal aging by studying defensive behaviors triggered by looming stimuli, which are linked to early AD pathology in the midbrain region. The 2-year...