The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded a $499,968 Project Grant to Pascall Systems, Inc. to develop an integrated brain state monitoring system for personalized anesthesia decision support. The goal is to prevent post-operative delirium in elderly surgical patients, particularly those at risk for Alzheimer's or related dementias.
Specifically, the project aims to: 1) establish technical feasibility of integrating the brain monitoring system with electronic medical records, infusion pumps, and anesthesia machines; 2) develop the next-generation integrated brain monitoring system to FDA submission readiness; and 3) create clinical decision support features, including age-compensated brain state tracking, anesthetic dose guidance, and delirium risk prediction. The project will validate these features using Pascall's extensive datasets from prior studies. The award period runs from August 2024 to January 2025.
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