Spatial single cell analysis of the human alzheimer's disease brain

Ended Project Grant Awarded Last action

Award ID
R44AG085832
Recipient
Awarding agency
Obligated
$2,458,626

Award facts

Assistance listing
93.866 Aging Research
Completion date
Originally
Place of performance
California, USA

Award details come from USAspending.gov.

Description

Abstract
The major goal of this project is to study human alzheimer's disease (ad) brains using the spatial genomics geneps instrument for automated large scale gene expression analysis at single cell resolution. At spatial genomics, we are commercializing the sequential fluorescence in situ hybridization (SEQFISH) technology (ENG ET AL, 2019) that allows thousands of genes to be imaged directly in brain samples. We have experience working with human brains with our SEQFISH technology and will hone the technology for use in human brains. Using the SEQFISH method, we will identify changes in cell types, spatial organization of groups of cells, and signaling interactions between neighboring cells in the human ad brain.

Transactions

Action Obligated Date
Amendment $0
Amendment $1,229,313
Original award $1,229,313

Quick answers

Who received award R44AG085832?

R44AG085832 was awarded to Spatial Genomics, Inc. by National Institute on Aging (National Institutes of Health) on September 21, 2023.

How much is award R44AG085832 worth?

$2,458,626 has been obligated on R44AG085832.

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