This federal Project Grant award of $333,810 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) aims to develop the RMT Complete, an all-in-one respiratory muscle training device and mobile application. The RMT Complete is designed to enhance breathing function and quality of life for patients with chronic obstructive pulmonary disease (COPD) by combining features such as an integrated manometer, wide resistance training...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $604,750 SBIR Phase I project grant (CFDA 93.837 - Cardiovascular Diseases Research) to Scientific Horizons Consulting LLC to develop a novel inhalation device and pulmonary delivery platform for anti-inflammatory agents to manage pain associated with chronic obstructive pulmonary disease (COPD). The project aims to investigate the feasibility of aerosolizing and delivering corticosteroids and non-steroidal anti-inflammatory drugs...
This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $1,107,276 to Lasarrus Clinic And Research Center Inc. to develop a mobile health system for remote monitoring of patients with Chronic Obstructive Pulmonary Disease (COPD). The project aims to enhance patient adherence to remote monitoring and early symptom recognition, in order to reduce COPD readmissions and healthcare costs. The system utilizes a wearable...
This Project Grant award from the National Science Foundation (NSF) under the Partnerships for Innovation - Research Partnerships (PFI-RP) program supports the development of a virtual human testing platform for inhaler innovation and drug delivery optimization. The $549,999 project, awarded on August 1, 2023 and running through July 31, 2026, aims to create an AI-assisted virtual platform that can accurately simulate airflow, aerosolized medication delivery, and drug translocation in both...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $499,966 to Koronis Biomedical Technologies Corp. (KBT) to commercialize a low-cost, portable device using the Forced Oscillation Technique (FOT) for respiratory assessment. The proposed FOT device requires minimal patient effort and skill, making it suitable for occupational health screening, physician office use, and home...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), will evaluate the use of mobile devices to extract vital signs to monitor patients with asthma. The $459,127 award to M5 Enterprise, LLC (doing business as Emedical Sentry) aims to improve the detection and management of asthma attacks through remote patient monitoring. The goal is to enhance telehealth by incorporating video-based vital sign...
This federal Project Grant award of $725,088 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) aims to optimize the effectiveness and implementation of COPD self-management treatment. The primary goal is to conduct a factorial optimization trial among 448 individuals with COPD to evaluate the impacts of treatment components including self-management education, physical activity, and inhaler training on respiratory-related hospitalizations and...
This Cooperative Agreement award from the Food and Drug Administration (FDA) under the FDA Research program (CFDA 93.103) provides $549,485 to Oklahoma State University (OSU) to develop advanced computational models integrating computational fluid dynamics, discrete element method, and machine learning to quantify variability in inhaler design, drug formulation, and user factors affecting the comparability and bioequivalence of generic orally inhaled drug products (OIDPs). The key objectives are...
This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), will fund the development and evaluation of the AirPen, a novel device designed to facilitate diaphragmatic breathing interventions for stress management among college students. The $294,312 award will support the following key objectives over the 1-year project period: Refine the AirPen intervention...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $295,924 to Convergent Engineering, Inc. to develop a prototype decision support system for personalized mechanical ventilation care. The system aims to simplify the use of esophageal pressure measurements to optimize ventilator settings and prevent complications for ventilated patients. The project has two key objectives: 1) Building a...