This $100,000 Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program will support the development of an advanced wound care technology at Florida International University. Specifically, the university will create a bandage-integrated platform that provides feedback-mediated wound therapy to enable personalized care. The conformable platform is designed to non-invasively monitor multiple wound biomarkers in spatial detail and then apply targeted...
The University of Miami School of Medicine is conducting a R21 research project titled "Developing Biomarkers of Healing and Non-Healing VLUs" under a $371,470 award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). The project aims to identify protein biomarkers in wound fluid that can predict healing outcomes and monitor progression of venous leg ulcers (VLUs), a common chronic wound condition. The researchers will analyze discarded wound...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $2,433,408.00 to Global Biomedical Technologies LLC to develop and validate an adhesive acrylic surgical drape for use in negative pressure wound therapy (NPWT) applications. The project aims to compare the performance and clinician acceptability of the company's...
This $250,000 National Science Foundation project grant supports the development of a microneedle-mediated adaptive phototherapy wound dressing by the University of South Florida from October 1, 2022 to November 30, 2024. The dressing integrates self-diagnosis and treatment tailored to wound conditions without external electronics or medical professionals. Microstructured microneedles act as optical waveguides to deliver localized blue or red light therapy at wound sites, changing wavelength...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is providing $208,125 to the University of Connecticut Health Center to develop an intralesional drug delivery strategy for treating infected wounds. The key products and services to be delivered include: Characterization of in situ formed microneedle-like drug depots and...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support Rhaeos, Inc. in the development of wearable sensors for continuous, noninvasive monitoring of wounds in older adults. The $613,044 award will enable Rhaeos to develop a conformal thermal sensor (CTS) capable of tracking key biomarkers of wound healing, including temperature and moisture balance, in real-time. The project aims to create a biomedical device suitable for out-patient...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to advance the understanding of how nanogenerator-driven electrical stimulation can accelerate wound healing. The $469,766 project will investigate the cellular-level mechanisms underlying this approach and identify optimal signal and device designs to deliver the desired therapeutic effect....
This $205,000 project grant from the National Institutes of Health's National Institute on Aging will fund research into the pathomechanics of diabetic foot ulcers at The University of Texas Southwestern Medical Center over a 12-month period. The research aims to identify more accurate markers and marker combinations for foot ulceration risk in patients with diabetic neuropathy and a history of prior ulcers. Using specialized equipment, the study will quantify two primary ulcer-causing...
The National Institute of General Medical Sciences (NIGMS) awarded a $801,650 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Illinois for the project "Spatio-Temporal Cellular Dynamics Regulating Differential Healing Outcomes". The goal is to use state-of-the-art single cell and spatial sequencing technologies combined with a new analytical framework to systematically compare cell type dynamics, cell-cell interactions, and...
This $1,017,602 National Science Foundation project grant supports research at North Carolina State University to develop microphysiological models for evaluating the role of age-dependent fibrinogen sialylation in wound healing. The three-year award under the NSF Engineering program (CFDA 47.041) will fund the creation of innovative tissue engineering techniques and microfluidic systems to study interactions between platelets and fibroblasts during wound healing. Researchers aim to better...