A telehealth intervention to increase screening and treatment for alcohol use disorder

Ended Project Grant Awarded Last action

Award ID
R44AA030702
Recipient
Awarding agency
Obligated
$2,982,950

Award facts

Assistance listing
93.273 Alcohol Research Programs
Completion date
Originally
Place of performance
California, USA

Award details come from USAspending.gov.

Description

Abstract
RIA health is a nationally scaling early-stage telemedicine and technology company that treats alcohol use disorder with a combination of objective measures of drinking (twice daily breathalyzer measures through our APP), physician-supervised medications, and group and individual coaching - the RIA treatment platform. RIA has enrolled more than 4,500 patients, is available in 45 states, and is covered by major insurers. RIA has accumulated more than 300K breathalyzer measures from enrolled patients that demonstrate a reduction in alcohol use of 50% at 1 month and 75% at 12 months. Mean retention in treatment is 10 months. The incidence and burdens of alcohol-associated liver disease are growing. There are no automated methods that screen specifically for early alcohol-associated liver disease. In this project we will use a large electronic health record system (epic at stanford university health) to identify patients with elevated liver function tests who are at increased risk for occult alcohol use disorder. A feasibility analysis of epic records at stanford identified >56,460 adult patients with elevated liver function tests (AST, ALT, GGT) who could be screened for this study. Patients with elevated liver function tests will be invited by an "honest broker" to be screened for alcohol use disorder and, if alcohol use disorder is present, to receive treatment through RIA. We hypothesize that patients with alcohol use disorder and elevated liver function tests who would otherwise not seek treatment will be motivated to engage in treatment. We will conduct a randomized wait-list controlled study in 124 subjects to demonstrate the efficacy of the RIA treatment platform. A comprehensive set of outcome measures will be assessed, with percent of subjects without heavy drinking in the final 4 weeks defined as the primary outcome. The project has several innovative features. IT is the first to use mass screening of a large electronic health records system to identify potential cases of alcohol use disorder with abnormal liver function tests and to engage them in treatment. Given the morbidity and mortality of alcohol use disorder, new methods to identify and engage these patients earlier are urgently needed. We will also conduct the first randomized controlled trial of the RIA treatment platform, providing crucial validation for payers.

Transactions

Action Obligated Date
Amendment $0
Amendment $943,481
Amendment $886,202
Amendment $886,202
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Amendment $0
Original award $267,065

Quick answers

Who received award R44AA030702?

R44AA030702 was awarded to Ria Technology Management Inc. by National Institute on Alcohol Abuse and Alcoholism (National Institutes of Health) on September 19, 2022.

How much is award R44AA030702 worth?

$2,982,950 has been obligated on R44AA030702.

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