Danfreez: zebrafish genetically-optimized for cryogenic storage of embryos
Ended Project Grant Awarded Last action
- Award ID
- R43OD032090
- Recipient
-
Invivo Biosystems, Inc. UEI RDHNFKDYX5X3
- Awarding agency
-
Aggregate Financial Assistance Data
National Institutes of Health, Department of Health and Human Services
- Obligated
- $929,310
Award facts
- Assistance listing
- 93.351 Research Infrastructure Programs
- Completion date
- Originally
- Funding agency
- Office of the Director National Institutes of Health, Department of Health and Human Services
- Place of performance
- Oregon, USA
Award details come from USAspending.gov.
Description
- Abstract
- Unlike C. Elegans and mice, methods for cold storage of zebrash lines are lacking in the marketplace. We propose the use of environmental and gene C factors to enable cold storage of viable embryos at frozen or near freezing condi ONS. In aim 1 we will explore the use of transient protein expression to produce proteins associated with anhydrobio C status. In aim 2 we explore the induc on of genes involved in diapause in killish as a mechanism to promote cold-storage survival. In aim 3, we will look at combina ONS of gene C and environmental factors that promote reanima on of zebrash embryos from cold storage. Achievement of any one of these aims that result in high viability yields from cold storage can then be developed in phase II as a gene cally integrated line, which can then be broadly commercialized as a product or service to aid researchers in their biobanking eorts with their zebrash lines.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $464,655 | |
| Original award | $464,655 |
Quick answers
Who received award R43OD032090?
R43OD032090 was awarded to Invivo Biosystems, Inc. by Aggregate Financial Assistance Data (National Institutes of Health) on August 15, 2022.
How much is award R43OD032090 worth?
$929,310 has been obligated on R43OD032090.
Which agency awarded R43OD032090?
Aggregate Financial Assistance Data (National Institutes of Health) awarded R43OD032090, with funding from Office of the Director (National Institutes of Health).
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