Project Grant R43NS145940
- The U.S. National Institute of Neurological Disorders and Stroke (NINDS) awarded a $125,685 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Leland Stanford Junior University (Stanford University). The funding will support the development of an injectable hydrogel with an integrated urokinase plasminogen activator (uPA) motif and plasmid DNA (pDNA) platelet-derived growth factor B (PDGFB)-lipoplexes to be loaded into the...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $147,486 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Massachusetts Institute of Technology (MIT) from July 1, 2025 to June 30, 2027. The grant funds the development of a novel Magnetic Resonance Imaging (MRI) method to concurrently measure brain tissue displacement, blood dynamics, and cerebrospinal fluid (CSF) flow in humans. This research...
- This Project Grant award of $704,313 from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, aims to advance a prognostic and monitoring biomarker of neutrophil-driven secondary brain injury in spontaneous intracerebral hemorrhage. The primary objective is to define and validate a standardized protocol to detect specific neutrophil biomarker levels as a potential prognostic and...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $373,778 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Research Foundation For The State University Of New York (Stony Brook University) to establish a novel vasculature database and analytical platform for mouse brain vasculature. The project aims to develop topology-preserving vessel segmentation algorithms and advanced statistical models...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $299,982 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Unandup, LLC, a technology development firm in St. Louis, Missouri. The grant funding supports the development of the Commercialization Readiness Pilot for the FAST (Flow Acceleration for Stroke Thrombolysis) System, an innovative medical device platform designed to safely accelerate the...
- The federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $439,239 to the Beckman Research Institute of the City of Hope to fabricate and evaluate the feasibility of a novel neurosurgical device termed "REMIDE" for the efficient and consistent removal of intracerebral hematomas using minimally invasive, image-guided...
- This $234,750 Project Grant award from the National Institute of Neurological Disorders and Stroke (CFDA 93.853) supports research at Emory University in Georgia focused on developing an instantaneous digital subtraction angiography (IDSA) technique for neurovascular applications. The research aims to overcome key clinical challenges associated with current intra-arterial digital subtraction angiography (IA-DSA) procedures, such as motion artifacts, risk of complications, and contrast-induced...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $431,750 to support a collaborative research project between Henry Ford Health and Michigan State University Health Sciences. The project aims to overexpress the CYP2C11 enzyme in peri-lesion astrocytes using an adeno-associated virus (AAV) vector, in order to increase cerebral...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $671,988 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Winifred Masterson Burke Medical Research Institute, Inc. The project focuses on understanding the cross-talk between two cell death pathways, sarmoptosis and ferroptosis, in the context of intracerebral hemorrhage (ICH), a type of stroke. The research aims to explore how the accumulation...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $1,375,478 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the J. David Gladstone Institutes in California. This grant funding supports a multidisciplinary research program to study the role of neurovascular dysfunction in neurodegeneration, CNS repair, and glial cell biology. Key research activities include in vivo two-photon and super-resolution...
The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, awarded a $314,363 project grant to Arsenal Medical, Inc. in Waltham, MA. The grant, with an award date of August 1, 2025 and a completion date of July 31, 2026, will fund the development of an engineering model of the middle meningeal artery embolization procedure for treating chronic subdural hematoma (CSDH), a neurological disorder. The model is intended to serve as a training tool for clinicians on the use of various embolic agents for this minimally invasive endovascular procedure, which has shown promise in reducing recurrence rates compared to traditional surgical evacuation.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $314.4k | 7/30/25 |