Project Grant R43NS117244

This $1,199,991 Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program aims to develop novel technologies for real-time assessment of blood clot properties to improve stroke treatment. The key products and services under this grant include: Integration of a sub-millimeter Raman fiber probe into a catheter for intravascular, in-vivo measurement of clot chemical composition. Training of a convolutional neural network to...

Federal Project Grant Award Summary The University of Pennsylvania received a $664,458 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective September 1, 2025, through August 31, 2030. This award supports the development and validation of a novel optical imaging technology for prehospital detection of large vessel occlusion (LVO) in acute stroke...

Federal Cooperative Agreement Summary Asterion AI Inc. received a $1.25 million Cooperative Agreement award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships program (CFDA 47.084), effective August 1, 2025 through July 31, 2027. The awardee will develop and validate an electroencephalogram (EEG)-based software product designed for pre-hospital stroke triage and detection of large vessel occlusion (LVO) strokes. The deliverables include expansion of a...

Grant Award Summary Yale University received a $503,626 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded May 19, 2026, with completion targeted for April 30, 2028. The Stroke-Clock Study will conduct proteomics research to identify and validate blood-based plasma protein biomarker panels capable of estimating stroke symptom onset time and...

Federal Project Grant Award Summary Weill Medical College of Cornell University received a $678,471 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), awarded June 1, 2026, with completion targeted for March 31, 2030. The award supports the development of a compact, portable transcranial Doppler (TCD) ultrasound device capable of...

Project Grant Summary The University of Texas at Austin received a $541,700 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded June 12, 2026, with completion targeted for May 31, 2031. The project develops advanced quantitative three-dimensional imaging techniques for measuring cerebral blood flow (CBF) during stroke. Specifically, the research...

Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $233,280 to the Regents of the University of Michigan on March 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This five-year project, directed by Dr. Brian Stamm at the Ann Arbor campus, addresses critical delays in acute ischemic stroke treatment delivery via telestroke services. The research will identify...

AWARD SUMMARY The University of Texas at El Paso received a $250,000 Project Grant from the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR, CFDA 93.433) awarded September 1, 2025, through August 31, 2028. The project will conduct a longitudinal, single-blind, randomized controlled non-inferiority trial evaluating Tele-CPASS, a telerehabilitation adaptation of the Critical Periods After Stroke (CPASS) intervention, against in-person CPASS therapy for...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant of $275,000 awarded to Xtract Medical Inc. aims to develop and demonstrate the feasibility of a novel catheter-based system for improved removal of blood clots during mechanical thrombectomy procedures to treat venous thromboembolism (VTE). The proposed system is designed to effectively remove large blood clots while minimizing damage to blood vessels and reducing complications such as...

The National Institute of Neurological Disorders and Stroke (NINDS) awarded Stanford University a $17.24 million Cooperative Agreement on August 13, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct the Cilostazol for Prevention of Recurrent Stroke (CLARITY) study. This clinical research initiative investigates long-term secondary stroke prevention through cilostazol therapy, a medication that prior Japanese trials...