The National Institute of Mental Health (NIMH) awarded a $449,228 Project Grant (CFDA 93.242 - Mental Health Research Grants) to Neuronexus Technologies, Inc. (doing business as Nuvectra) to develop an integrated system for chronic extracellular neural recording and stimulation in human brain organoids. The key objectives are to: 1) create a biological assay chamber supporting long-term electrophysiology while maintaining organoid health, 2) develop high-fidelity 3D neural probes for chronic recording and stimulation, and 3) deliver an integrated system for turn-key longitudinal electrophysiological assays in brain organoids. This project aims to provide a non-destructive, label-free method to longitudinally study functional neural activity and its relationship to molecular/cellular features in brain organoids, supporting neuroscience research and therapeutic development. The award period runs from March 1, 2025 to February 28, 2027.
Generated 3/18/25, 2:03 AM