Project Grant R43MH101958

This federal Project Grant award of $460,500 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) is aimed at developing novel bioprinting methodologies for the production of human stem cell-based organoids. The key objectives are to: 1) Create a customized bioink formulation using proteins, polysaccharides, and functionalized nanoparticles to foster the...

Federal Project Grant Award Summary The Salk Institute for Biological Studies received a $150,104 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded February 1, 2026, with completion targeted for October 31, 2028. Under the mentorship of Dr. Fred Gage, the Institute will develop and deliver an advanced in vitro methodology for cultivating brain...

Federal Grant Award Summary Bioprinting Laboratories Inc. received a $306,872 Project Grant award from the National Institute of Environmental Health Sciences under the Environmental Health program (CFDA 93.113), effective July 8, 2025, with a completion date of June 30, 2026. The award funds development of a high-throughput testing platform for assessing developmental neurotoxicity (DNT) using engineered brain organoids. The company will establish genetically modified induced pluripotent stem...

Brains Minds and Machine Advanced Research Training Course The National Institute on Drug Abuse (NIDA) awarded The Marine Biological Laboratory (MBL) a Project Grant of $611,254 under the Drug Use and Addiction Research Programs (CFDA 93.279) for the period August 1, 2025 through July 31, 2028. The award supports the delivery of an advanced in-person research training course conducted at MBL's facility in Woods Hole, Massachusetts. The course is designed to cultivate a community of scientific...

The National Institute of General Medical Sciences (NIGMS) awarded a $275,756 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Rewire Neuroscience LLC, a woman-owned small business in Oregon. The funding supports the development of PipSqueak Pro, an AI-powered computer vision platform that aims to democratize access to advanced machine learning techniques for automated biomedical image analysis. The platform seeks to reduce human bias, subjectivity,...

This federal Project Grant award of $446,126 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a new bioassay to study astrocyte borders and profile their functional states in the context of diverse non-neural cell populations. The key objectives are to optimize the bioassay by combining injectable cellulose-based hydrogels with viral vectors to...

This federal Project Grant award, totaling $2,683,965.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports the establishment of a human microphysiological system to elucidate cellular mechanisms underlying vulnerability to Alzheimer's disease (AD). The grant recipient, Brigham & Women's Hospital Inc., a subsidiary of Partners Healthcare...

This $500,000 Project Grant was awarded on September 15, 2024 by the National Institute on Aging (CFDA 93.866 Aging Research program) to Neucyte Inc., a minority-owned small business specializing in advanced biomedical research and development. The funding will support the development of a miniaturized "mini-brain" microphysiological system (MPS) platform using Alzheimer's disease (AD) patient-derived cells. The goal is to create a scalable, reproducible in vitro brain model that can...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Brainstorm Therapeutics, Inc. aims to develop and validate a novel Parkinson's disease drug discovery platform using patient-derived midbrain organoids. The platform will guide therapeutic candidate identification, patient selection, and trial endpoint refinement to accelerate the development of effective disease-modifying Parkinson's treatments. Key innovations...

The Trustees of Columbia University in the City of New York (Columbia University), through its Health Sciences Division, was awarded a $445,009 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The grant's objective is to develop approaches for introducing developmentally-relevant inputs and reading out neuronal activity in human brain organoids to...