Project Grant R43HL151549

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to advance geriatric palliative care by assessing the feasibility and acceptability of using radio frequency (RF) sensors to capture cardiopulmonary measures in nursing home patients with Alzheimer's disease and related dementias (ADRD). The $451,721 award to Weill Medical College of Cornell University will also develop a machine learning algorithm to autonomously detect and predict respiratory...

This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $780,466 to quantify the integrity of sleep-dependent memory processing in pathological aging and Alzheimer's disease, with the goal of developing inexpensive electroencephalographic (EEG) wearable applications for monitoring brain health and detecting early neurodegenerative changes. The key products and services being delivered under this 5-year award, which began on December 15, 2024,...

This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $678,710 to validate a novel multi-sensor machine learning approach for precision sleep tracking in nightshift workers. The key products/services to be delivered include: Validation of a multi-sensor machine learning system to accurately track sleep patterns in nightshift workers, an underserved population critical to public...

This $608,826 Project Grant awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) will develop a new class of wireless, skin-conformable, and dual-sensing wearable system to monitor voice and upper airway (VUA) health. The key products and services to be delivered include: A single neck-worn wearable device that uses neck surface accelerometry and surface electromyography to...

This $740,271 federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), aims to address the problem of undiagnosed obstructive sleep apnea (OSA) in primary care clinics. The primary awardee, The Ohio State University, will lead a multi-year research effort to: Determine the prevalence of OSA and its subtypes, as well as the rate of OSA underdiagnosis, in primary care practices. Conduct a root cause...

The National Heart, Lung, and Blood Institute (NHLBI) awarded a $1,231,242 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Powell Mansfield, Inc. in San Diego, CA. The grant funding will support the development and validation of a new diagnostic tool called Deep Learning-Enhanced Transmembranous Electromyography (DL-TMEMG) for the accurate detection of Obstructive Sleep Apnea (OSA). The project aims to establish the feasibility of using TMEMG and deep learning...

This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), supports the development of an innovative mobile health system for remote monitoring of patients with chronic obstructive pulmonary disease (COPD). The $1,052,276 award to Lasarrus Clinic And Research Center Inc. will fund a longitudinal study to validate a wearable, multimodal sensor device called "WearMe" that can continuously...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $1,498,158.00 to Synaptic Health LLC to develop a novel closed-loop feedback neuromodulation system to improve slow wave sleep in Alzheimer's disease patients. The project aims to create a prototype device that can sense sleep architecture and provide peripheral neuromodulation stimulation to individuals over age 65 who are at elevated risk of Alzheimer's disease. The goal is to demonstrate that...

This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $299,893 to Pascall Systems, Inc. to develop a novel system that combines pre-operative cognitive assessment with Pascall's FDA-cleared wireless EEG technology for intraoperative monitoring. The goal is to enable personalized anesthesia care and effective monitoring of postoperative neurocognitive disorders (PNDs) in elderly surgical patients. The key products and services to be delivered...

The Department of Health and Human Services' National Institutes of Health's National Institute on Aging awarded $865,905 under the Aging Research program (CFDA 93.866) to Careband, Inc. to develop the Appraise to Assist system. This project grant will support Careband and its partner Eperture LLC to engineer a system integrating Careband's wearable device and Eperture's tablet platform. The system aims to passively and unobtrusively monitor, empirically measure, and facilitate engagement...