Project Grant R43HL134450

The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), awarded a $1,024,635 project grant to Corvion, Inc. to develop a Totally Implanted Left Ventricular Assist Device (TI-LVAD). The TI-LVAD aims to reduce complications and enhance quality of life for heart failure patients by eliminating the need for a percutaneous driveline and external power supply. The key innovation is a hybrid magnetically levitated blood pump that requires...

Federal Project Grant Award Summary Perfusion Solutions Inc. received a $320,838 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded on September 5, 2025, with a completion date of February 28, 2027. The grant supports the development of a fail-safe, high-output cavopulmonary assist device designed to provide mechanical circulatory support for pediatric and adolescent patients with single ventricle...

This $8.7 million project grant from the Department of the Army Medical Command, under the Military Medical Research and Development program (CFDA 12.420), supports the development of patient care technologies for permanent ambulatory artificial lung support from May 2022 to April 2026. Carnegie Mellon University is the primary awardee and will develop technologies to transition a pulmonary assist system to long-term support of chronic lung disease patients. Vanderbilt University Medical...

Federal Project Grant Award Summary Pranions, Inc. received a $2,426,364 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded August 1, 2025, with a completion date of July 31, 2027. The award supports development of a next-generation, high-flow portable oxygen concentrator (POC) designed to address significant limitations in existing commercial devices used by approximately 1.5 million Americans with...

This K23 Mentored Career Development Award, funded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), supports Dr. Vail's research at the University of Pennsylvania to evaluate the broader impacts of deceased organ donor centralization on lung transplantation outcomes. The $174,420 award, initiated September 1, 2025, and extending through July 31, 2030, funds investigative services examining how the concentration of donor...

This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships program) provides $274,274 to X-Cor Therapeutics Inc., a minority-owned small disadvantaged business in Washington, DC, to develop a novel respiratory dialysis system for treating chronic obstructive pulmonary disease (COPD) patients. The project aims to optimize a prototype that can efficiently remove excess carbon dioxide from the blood of COPD patients, with the goal of...

Federal Grant Award Summary Respair, Inc. received a $305,218 Small Business Innovation Research (SBIR) Phase I Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded on September 15, 2025, with completion targeted for August 31, 2026. The award funds development and feasibility assessment of AssuranceET, a novel pediatric endotracheal tube (ETT) designed to replace traditional inflatable balloon...

Federal Project Grant Award Summary Airalux Medical, Inc. received a $306,872 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 5, 2025, with completion targeted for September 4, 2026. The award funds development and commercialization of a digital incentive spirometry device designed to improve patient adherence and clinical workflow efficiency in post-operative lung complication...

Federal Grant Award Summary Georgia TECH Research Corp received a $709,172 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 1, 2025, through June 30, 2030. This award funds the development and validation of next-generation 3D printed airway splints designed to treat tracheobronchomalacia (TBM), a condition characterized by dynamic airway collapse in children. The research will deliver...

This $7,836,599.00 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) will support the development of a novel centrifugal left ventricular assist device (LVAD) with wireless power transfer and anti-thrombotic coating technology. The prime awardee, Georgia Tech Research Corporation, will lead the research and development efforts, which include fabricating and characterizing slippery hydrophilic (SLIC) coatings to improve...