Project Grant R43HL126469

This Project Grant, awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), supports the development of an unbiased pulse-oximetry method to address documented skin-tone bias in conventional oxygen saturation measurements. Obligating $134,537 with a performance period from September 5, 2025, through June 30, 2030, the award funds research conducted by Trustees of Tufts College in Medford, Massachusetts. The research...

This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to Makani Science Inc. will develop a continuous respiratory monitoring platform to accurately classify apnea of prematurity (AOP) in premature newborns. The $371,021 award will fund a two-phase effort to build a multimodal monitoring system and machine learning models to identify the major AOP types (central, obstructive, and mixed). The initial R61 phase will develop the...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Cooperative Agreement award for $997,142 aims to develop a rapid phenylalanine blood level monitor for patients with phenylketonuria (PKU), a lifelong genetic disorder. The product consists of a test strip and device that can provide frequent, accessible monitoring of phenylalanine levels from a finger prick to improve disease management and patient outcomes. The project focuses on optimizing the...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $374,378 to Michigan State University to develop a computational modeling framework for a miniaturized, noninvasive, wireless, luminescence-based carbon dioxide sensing wearable device. The goal is to accurately translate transcutaneous partial pressure of CO2...

The National Heart, Lung, and Blood Institute (NHLBI) awarded a $269,922 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Steth X Microsystems Inc. to develop a smart, wearable contact microphone patch for extended and remote monitoring of lung functions. The goal is to create a low-profile, battery-powered wireless device capable of accurately detecting and quantifying adventitious lung sounds as well as breathing abnormalities in patients with respiratory...

Federal Grant Award Summary Award Overview: The National Heart, Lung, and Blood Institute (NHLBI) awarded Actiox LLC a $699,468 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) for development and validation of a wearable microneedle-based biosensor for continuous cardiac troponin I (cTnI) monitoring. The award was obligated on September 10, 2025, with a completion date of October 31, 2026, and will be performed at the company's La Jolla, California facility....

Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $234,000 Project Grant to the University of Colorado-Denver, effective September 1, 2025, through August 31, 2027, under the Cardiovascular Diseases Research program (CFDA 93.837). The research will directly measure skin pigmentation in study subjects to evaluate and mitigate documented bias in pulse oximetry accuracy. The project addresses a critical gap identified by the U.S. Food and Drug...

Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Washington University a Project Grant totaling $639,165 (awarded May 15, 2025; completion February 28, 2030) under the Cardiovascular Diseases Research program (CFDA 93.837) to develop an equitable and accessible wearable device for continuous calculation of blood loss related to postpartum hemorrhage (PPH). The project addresses the critical clinical challenge that PPH represents the leading cause of...

The Consumer Product Safety Commission awarded a $125,000 Project Grant to the County of Rockland, New York under the Nicholas and Zachary Burt Memorial Carbon Monoxide Poisoning Prevention Grants program (CFDA 87.003). The two-year grant, with a performance period from June 28, 2024 to June 27, 2026, will support the county's efforts to reduce carbon monoxide (CO) poisoning risks in residential settings. The funding will be used to purchase and install CO alarms, develop training programs,...

Pons Incorporated received a $337,355 Project Grant award from the National Institute for Minority Health and Health Disparities under the Minority Health and Health Disparities Research program (CFDA 93.307) on September 17, 2025, for development of an automated image enhancement system to improve point-of-care ultrasound (POCUS) imaging in out-of-hospital settings. The project, scheduled for completion by August 31, 2026, addresses documented disparities in liver disease diagnosis and...