Project Grant R43GM161329
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of Fluorofinder's "Matched Pair Tool", an innovative digital workflow solution designed to streamline the identification of commercially available antibody pairs for improved immunoassay development. The $348,492 award, made on July 2, 2025, aims to create a tool that will enable efficient searches...
- The National Institute of General Medical Sciences (NIGMS) awarded a $349,243 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Imagen Bioworks Inc. on September 12, 2025. The grant supports the development of an innovative "Spotlight-Omics" workflow that can cost-effectively isolate disease-relevant spatiotemporal phenotypes from live cell cultures for subsequent omics analysis. This workflow aims to address a critical limitation of current...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $330,076 to Trestle Optics LLC, a small disadvantaged business located in Irvine, California. The award supports the development of a novel photothermal microscopy platform integrated with spatial light interference imaging. This innovative instrument is designed to enable non-destructive profiling and mapping of...
- The National Institute of General Medical Sciences (NIGMS) awarded a $333,048 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Imagen Bioworks Inc. in Houston, TX. The goal of this 1-year project is to develop a versatile 2-photon microscopy platform, dubbed 2P-SPOTLIGHT, to isolate individual cells from 3D tissue samples and 3D cell cultures based on their spatial and temporal properties. This will enable researchers to conduct downstream multi-omics...
- The National Institute of General Medical Sciences (NIGMS) awarded a $306,872 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Fluid Discovery, Inc., a San Francisco-based biotechnology company, to develop a "Universal Platform for Ultrahigh-Throughput Biocatalyst Evolution with Micro-Mass Spectrometry." The award supports the development of a commercial prototype for Fluid Discovery's novel screening platform, which combines scalable hardware,...
- The National Institute of General Medical Sciences (NIGMS) awarded a $290,536 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to Trestle Optics LLC, a small disadvantaged business, to develop a novel high numerical aperture catadioptric lens for ultra-broadband multimodal microscopy. This lens will enable advancements in existing nonlinear optical imaging modalities, such as three-photon excited fluorescence and third-harmonic generation, by overcoming limitations of...
- The National Institute of General Medical Sciences (NIGMS) awarded Trestle Optics LLC a $305,647 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to develop a novel photothermal microscopy system for non-destructive, high-resolution screening and sorting of microalgae to identify and enrich strains producing high-value polyunsaturated fatty acids. The project aims to engineer and prototype a microfluidic platform integrating photothermal imaging...
- The National Institute of General Medical Sciences (NIGMS) awarded a $249,575 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University Enterprises, Inc. (UEI) at California State University, Sacramento. The award will fund the acquisition of a new Zeiss LSM 900 confocal laser scanning microscope to advance the research of three principal investigators studying the cellular and molecular aspects of neurodevelopmental and neurodegenerative diseases....
- This federal Project Grant award of $349,280 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of advanced machine learning algorithms for ultra-high-density, ultra-high-precision single molecule localization microscopy (SMLM). The grant recipient, Xgenomes Corp., will create a SMLM video simulator to generate training data (Aim 1), build a machine learning-based grouping...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $410,014 Project Grant to Trustees of Boston University to establish proof-of-concept for a new high-speed, real-time feedback-driven single particle tracking (RT-FD-SPT) fluorescence microscope with concurrent spectroscopic readout. The goal of this project is to develop an advanced tracking approach that leverages dual-stage scanners and nonlinear...
The National Institute of General Medical Sciences (NIGMS) awarded Fluorofinder, LLC a $356,190 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to advance a novel microscopy workflow tool. The tool is designed to streamline assay development, improve awareness and education around optimal selection of microscopy assay components (instruments and reagents), and enhance reproducibility in the field. The project aims to address common challenges in microscopy, such as optimizing microscope component configuration and selecting validated reagents, to enable users to identify optimal experimental setups. This software-based solution is intended to reduce costs associated with wasted resources, improve experimental outcomes, and potentially address aspects of the reproducibility crisis in scientific research. The award has an effective date of Sep 4, 2025 and a targeted completion date of Sep 3, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $356.2k | 9/4/25 |