Project Grant R43GM161193
- This Project Grant award, made by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of Dermisphere, an advanced dermal regeneration scaffold product by Fesariustherapeutics Inc. The $349,345 award aims to demonstrate the feasibility of using Dermisphere to manage acute major burn wounds. Preliminary studies have shown that Dermisphere can support rapid and sustained cellular...
- The National Institute of General Medical Sciences (NIGMS) awarded a $349,910 Project Grant under CFDA 93.859 - Biomedical Research and Research Training program to Perfusio Corp. for the development of a "Multi-Spectral AI/ML Powered Burn and Wound Evaluation Technology Using a Cost-Effective Handheld Device". The project aims to create a portable, affordable, and user-friendly device that can provide real-time, dynamic physiologic data to medical providers for accurate assessment...
- This federal Project Grant award of $400,000 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research by Baylor College of Medicine to develop and optimize bioengineered polymers with tunable properties to modulate inflammatory responses in the wound microenvironment. The goal is to enhance tissue repair and regeneration across different wound types, particularly in chronic wounds where...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) aims to develop a hyperstable and bioactive FGF1-FGF2 dimer formulation for effective healing of diabetic skin wounds. The $435,226 award to the University of Arkansas will fund research activities across three key objectives: Designing a hyperstable and bioactive FGF1-FGF2 dimer and its variants, Developing injectable anionic...
- This $428,600 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports an investigation into how RNA-directed feedback loops coordinate wound healing and regeneration. The research project aims to understand the conserved developmental pathways and heterochronic genes that regulate cell migration, fate, and timing during normal adult wound repair and regeneration,...
- This $367,577 Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) to Adepthera LLC aims to develop a regenerative peptide therapy to accelerate pressure ulcer healing. Specifically, the award will fund research to identify an optimal formulation of a self-assembling adrenomedullin (ADM) analog gel that can improve local blood circulation and wound healing in aging and diabetic mouse models. The proposed therapy would be administered weekly or biweekly via...
- The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), awarded a $314,363 Project Grant to Gavia Bio, LLC to develop an antimicrobial peptide called DGL13K as a novel topical treatment for drug-resistant bacterial infections in burn wounds. The goal of this 1-year project is to progress the preclinical development of DGL13K by demonstrating its safety and efficacy as a broad-spectrum treatment for...
- This federal Project Grant award in the amount of $311,770.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award is supporting research at Vanderbilt University to investigate the mechanisms of tissue repair, with a focus on understanding epithelial repair and basement membrane repair. The research aims to advance knowledge of how cells coordinate migration, proliferation, and...
- The federal Project Grant award of $649,391 provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is supporting research to enhance healing after injury. The overarching objective is to define the mechanisms that restrain tissue regeneration in order to develop new therapeutics to improve healing of the gut and skin following injury or infection. The 5-year project, which...
- The National Institute of General Medical Sciences (NIGMS) awarded a $699,738 Project Grant under CFDA 93.859 (Biomedical Research and Research Training) to Sagespectra Inc., a minority and woman-owned business based in Conroe, TX. The grant supports the development and validation of a wireless patch for post-surgical monitoring and electrotherapy of surgical flaps. The key products and services to be delivered include: Design and development of a prototype wireless patch capable of real-time...
The National Institute of General Medical Sciences (NIGMS), through its Biomedical Research and Research Training program (CFDA 93.859), awarded a $349,892 project grant to Fesariustherapeutics Inc. to develop Dermisphere Shield, an antimicrobial dermal regeneration template for application in challenging wound environments. The project aims to create a dermal regeneration scaffold that promotes rapid cellular infiltration, angiogenesis, and accelerated wound healing, potentially offering significant improvements over existing wound treatment technologies. The grant will support the advancement of the Dermisphere technology through preclinical development, large animal studies, biocompatibility testing, and user validation, with the ultimate goal of achieving FDA 510(k) approval and initiating human clinical trials. The award has a performance period from Sep 1, 2025 to Aug 31, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/8/25 | ||
| Not listed | $349.9k | 7/31/25 |