Project Grant R43GM159468
- Federal Project Grant Award Summary Vivid Bioinnovations, PBC (operating as Fluid Discovery, Inc.) received a $306,872 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) for the period August 1, 2025 through July 31, 2026. The award supports development of a commercial prototype for an ultrahigh-throughput biocatalyst evolution platform that combines precision nanoliter fluid handling, label-free...
- Federal Project Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded Proteovista LLC a $306,151 Project Grant (CFDA 93.859: Biomedical Research and Research Training) on June 2, 2026, for the development of ClusterBuild, a novel platform designed to enable cost-effective, high-fidelity synthesis of large biosynthetic gene clusters (BGCs) up to 100 kilobases in size. The project, led by Principal Investigators Christopher L. Warren and Mary S. Ozers and scheduled...
- Federal Grant Award Summary Z Biotech, LLC received a $306,782 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2027. The award supports continued development and validation of Sialoglycan-Recognizing Probes (SGRPs)—engineered molecular tools designed to detect and characterize sialoglycans on cell surfaces and secreted molecules with...
- Federal Project Grant Award Summary Michigan Technological University received $383,801 from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859) for a five-year project spanning May 1, 2026, through February 28, 2031. The award funds development of a cost-effective, scalable, multiplexed biosensing platform based on molecularly imprinted polymers (MIPs) for rapid biomarker detection. The research addresses clinical...
- Federal Project Grant Award Summary Molecular Instruments, Inc. received a $306,788 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) with an award date of September 30, 2025, and a completion date of September 29, 2026. The award supports the development and advancement of probe technology for ultrasensitive RNA imaging utilizing Hybridization Chain Reaction (HCR) methodology. The project...
- Federal Project Grant Award Summary Uforce Biotechnology, LLC received a $267,323 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) on May 15, 2025, with completion targeted for April 30, 2026. The award funds development of a quantum sensing device that integrates super-resolution force spectroscopy (SURFS) with ultrasound technology to accelerate drug development and improve screening...
- Federal Project Grant Award Summary Protabit LLC received $304,602 in Project Grant funding from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award, effective August 7, 2025, with completion targeted for July 31, 2026, supports the development of high-throughput engineering technologies for bispecific antibodies—therapeutic molecules that combine two different antigen-binding domains. The project...
- Federal Grant Award Summary Primary Bioscience, Inc. received a $305,000 Small Business Technology Transfer (STTR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) effective July 15, 2025, with a completion date of June 30, 2026. The company is developing an ultra-sensitive biosensor capable of single-molecule protein analysis and sequencing. The technology integrates a nanopatterned chip with a proprietary amino acid and...
- Federal Grant Award Summary Robust Diagnostics LLC received a $404,032 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2026. The award supports development of a machine learning-powered platform for accelerated discovery of peptide ligands for peptide-drug conjugates (PDCs), a targeted cytotoxic delivery approach designed to improve upon...
- Federal Project Grant Award Summary Nanoprobes Inc. received a $613,744 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 1, 2025, with completion targeted for February 28, 2027. The award funds the development of combined fluorescent and gold labeling reagents designed to advance correlative light and electron microscopy (CLEM) capabilities. The company will systematically...
Potomac Affinity Proteins, LLC received a $377,602 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2026 through June 30, 2027. The awardee is developing a protease chain reaction (PROCR) technology platform designed to enable rapid, highly sensitive, and quantitative detection of biomolecules through simplified mix-and-read assays. The core innovation centers on engineering protease-inhibitor complexes that generate self-amplifying signal cascades analogous to polymerase chain reaction amplification, with proteases concentrated into catalytic clusters that activate additional protease-inhibitor complexes in solution to produce substantial signal amplification in response to target molecule binding. During Phase I, the research team will optimize the engineered protease and inhibitor components to enhance catalytic turnover and validate the detection platform using three priority target molecules: gram-negative bacterial lipopolysaccharide (endotoxin), human interleukin-2 (IL-2), and human ferritin. The work will be conducted at the awardee's facility in Gaithersburg, Maryland, and is expected to advance molecular diagnostics by establishing a versatile detection technology applicable across multiple biomarker and pathogen identification applications.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $377.6k | 6/23/26 |