The National Institute of General Medical Sciences (NIGMS) awarded a $308,925 Project Grant (CFDA #93.859 Biomedical Research and Research Training) to Chemia Biosciences, Inc., a small disadvantaged business, to develop advanced computational technologies for discovering novel fungal natural products with potential antimicrobial, antifungal, and antitumor applications. The funding supports the creation of software tools that leverage high-throughput mass spectrometry and genome mining techniques to predict the molecular structures of natural products encoded in microbial genomes, with a focus on fungal species. The goal is to address the growing challenge of antibiotic resistance by identifying new classes of bioactive natural compounds. The software technologies developed under this award will be made available as a cloud service to research partners such as the University of Michigan's Natural Products Discovery Core, who will utilize the tools to screen and characterize potential new natural product leads.
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