Project Grant R43GM137652

This Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program totaling $511,798 was awarded to Kilele Health Inc. on June 15, 2022 to develop continuous diagnostic monitoring platforms beyond glucose sensing. Unlike existing enzymatic glucose sensors, the company will utilize electrochemical aptamer sensors that can rapidly measure other molecules in the body with high specificity and sensitivity. The aim is to address limitations that have...

Michigan Technological University received a $199,972 Project Grant award from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering (47.041) federal grant program. The award will fund the development of an electrochemical sensor to simultaneously detect glucose and cortisol using an enzyme-free and antibody-free approach based on electrochemically polymerized molecularly imprinted polymers. The sensor aims to provide...

The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $450,000 Project Grant to the Texas A&M Engineering Experiment Station (Tees) to develop an injectable, grain-of-rice size glucose biosensor for continuous blood sugar monitoring. The key products or services to be provided under this 3-year grant include: Developing an injectable glucose biosensor comprised of a self-cleaning membrane and a near-infrared fluorescence...

This $249,000 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), supports the development of a novel split enzyme diagnostic platform for rapid, sensitive detection of protein and small molecule biomarkers at the point of care. The key products and services to be delivered through this grant include: Incorporating binding domains...

The National Science Foundation (NSF) awarded a three-year, $449,999 Project Grant under their Engineering program (CFDA 47.041) to the University of Cincinnati to develop an implantable biosensor platform that can continuously monitor various biomarkers in the body for over a year. The project aims to create a new class of long-lasting aptamer-based sensors protected by robust porous oxide coatings, which would enable the first practical implantable monitoring system for managing chronic...

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $990,990 project grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Integrated Medical Sensors Inc., a minority-owned small disadvantaged business located in Irvine, CA. The project aims to optimize the manufacturing and quality framework for the company's miniaturized, integrated continuous glucose monitoring (CGM+) platform in preparation for larger human...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will support the development and in-vivo testing of continuous electrochemical aptamer sensors for monitoring large analytes like insulin, inflammatory markers, and cardiac markers. The $360,320 award to the University of Cincinnati will fund a 2-year research project with the...

This Project Grant award for $299,712 from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports the development of electrochemical aptamer-based (E-AB) sensors for the rapid and accurate detection of multiple cardiovascular disease (CVD) biomarkers. The University of South Carolina, with mentorship from collaborators at the University of Cincinnati, will design and characterize these multiplexed E-AB sensors to enable early diagnosis of CVDs, which are...

This $432,740 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to the Cal Poly Corporation supports the development of a new class of paper-based chronometric biosensors. The objective is to create quantitative point-of-care diagnostic tools that can detect a range of biological analytes, including disease markers, environmental contaminants, and security threats, using time as the sensing signal. The novel biosensors will leverage polymer...

This National Science Foundation (NSF) Biological Sciences grant award provides $2,225,964 to the Georgia Tech Research Corporation (Georgia Tech) to develop a novel biosensing platform called "protocell communities" that can be used for rapid, low-cost medical diagnostics. The project aims to create a tool that can diagnose medical conditions by detecting and integrating multiple indicator molecules, addressing limitations of single-analyte diagnostics. The protocell technology uses...