Project Grant R43GM131486

This Project Grant award of $686,000 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to develop an optimized, lead candidate tissue-adhesive endoscopic tattoo ink (TAT2) to overcome limitations of current commercial inks for marking gastrointestinal lesions. The new TAT2 ink is intended to demonstrate improved tissue retention, equivalent visual contrast, and reduced inflammatory potential...

The National Science Foundation awarded a $255,957 STTR Phase I Project Grant to CHS Healthcare Ventures Inc., doing business as Lightengale, to develop a lighted infusion line to optimize care and decrease complications for critically ill patients in infectious isolation situations such as COVID-19. The grant is funded through the NSF's Technology, Innovation, and Partnerships program (CFDA 47.084) and aims to advance science and engineering research leading to breakthrough technologies and...

This $256,000 National Science Foundation project grant supports the development of an automated chest tube to prevent clotting. Circulatech LLC will design and prototype a novel chest tube that proactively manages fluid flow within the catheter lumen to flush and drain the tube, reducing blood clot formation. Through a process called "dilutional coagulopathy," the tube will use sterile saline or anticoagulants to reduce thrombosis in the drainage space rather than relying on...

This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) provides $275,000 to Carrtech Corp, a woman-owned small business manufacturer, to develop an integrated, single-needle filter system to remove glass shards from injectable fluids. The project aims to create a novel, disposable, inline mechanical filter that addresses the current multi-step process healthcare providers must use to filter glass ampoules prior to injection,...

Visionaire Products, Inc. received a $256,000 Project Grant award from the National Science Foundation on February 15, 2021 to complete work by July 31, 2021. The grant was awarded under the NSF's Engineering program (CFDA 47.041) to support development of a novel, microfluidic device to improve collection and analysis of biopsy samples from ocular paracentesis procedures. Specifically, the funding enables Visionaire Products to advance a microfluidic technology designed to more efficiently...

F Square Medical LLC received a $880,668 Project Grant from the National Eye Institute of the National Institutes of Health, Department of Health and Human Services under the Vision Research federal grant program (CFDA 93.867) for the period of September 1, 2021 through August 31, 2022. The funding will support F Square Medical's development of the first-ever safe and effective anterior chamber paracentesis instrument to treat and diagnose ocular diseases. Specifically, the company will refine...

The National Science Foundation (NSF) awarded a Project Grant under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) to Lensguide Imaging Technology Inc. for $275,000 to develop a nano-optical imaging microendoscope for in vivo imaging. The project aims to create a hair-sized, 100 μm diameter microendoscope that can image at depths greater than 3 mm in live animals with subcellular resolution, overcoming limitations of current optical imaging technologies. This...

This National Science Foundation (NSF) Cooperative Agreement award under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,250,000 in funding to Biodevek Inc., a Boston-based small business, to develop a novel sprayable hydrogel sealant for managing gastrointestinal (GI) lesions and bleeding. The project aims to create a minimally invasive, bio-adhesive hydrogel solution that can provide sustained lesion protection and hemostasis, potentially reducing...

This Project Grant award from the National Eye Institute (NEI), under the CFDA program 93.867 Vision Research, is funding the development of an injectable optoacoustic retina prosthesis for high-precision retinal stimulation. The PI, Prof. Chen Yang, and Co-I, Prof. Serge Picaud, are leading a multi-disciplinary team to create a minimally invasive retinal prosthesis with micrometer-scale spatial resolution. The $1,765,704 award will enable the team to develop a biocompatible optoacoustic...

The National Institute of General Medical Sciences (NIGMS) awarded Trestle Optics LLC a $305,647 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to develop a novel photothermal microscopy system for non-destructive, high-resolution screening and sorting of microalgae to identify and enrich strains producing high-value polyunsaturated fatty acids. The project aims to engineer and prototype a microfluidic platform integrating photothermal imaging...