Project Grant R43GM109606

The National Science Foundation (NSF) awarded a $274,995 SBIR Phase I project grant under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) to Tiptek, LLC, a small for-profit limited liability company. The project aims to improve a critical semiconductor manufacturing method called nanoprobing by enabling the technique to probe smaller and more complex electrical devices for longer periods. The improved nanoprobes developed through this research will support the...

The National Institute of Standards and Technology (NIST) awarded a $289,999.65 Cooperative Agreement under the CHIPS Research and Development (CFDA 11.042) program to Tiptek, LLC, a for-profit limited liability company, to create new gigahertz nanoprobes for semiconductor failure analysis. Through this funding, Tiptek will build ultra-high-speed nanoprobe prototypes capable of operating at gigahertz frequencies to detect "soft" electrical faults that are difficult to identify with...

The National Science Foundation awarded $256,000 to Optave Diagnostics LLC through the Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a prototype endoscopic probe for molecular imaging and diagnosis of cancerous prostate pathologies. The 12-month project grant will support the creation of a medical device using photoacoustic imaging and acoustic lens technology to aid in the detection and diagnosis of prostate cancer. The proposed endoscopic probe offers an alternative...

This $275,000 project grant from the National Science Foundation's Engineering Directorate (CFDA 47.041) will fund the development of novel electronic-photonic silicon carbide neural probes for recording and stimulating neural activity. The Georgia Tech Research Corporation will receive funding on behalf of collaborating researchers to design penetrating neural probes made entirely of silicon carbide, a robust material proven to withstand the corrosive brain environment long-term. The probes...

This $255,991 National Science Foundation project grant supports the development of an automated system for rapid analysis of biopsy samples by Amcyt, Inc. The system aims to increase the efficiency and accessibility of fine needle aspiration biopsy procedures through three automated processes: sample smearing, staining, and image capture. This addresses a critical need to improve biopsy analytics and potentially eliminate up to 20% of failed procedures due to sampling errors. By automating...

This SBIR Phase I Project Grant award of $305,000 from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) is advancing semiconductor processing technology. The project aims to develop a novel power generator and applicator system that uses nanosecond-scale high voltage pulses to enhance the quality, reduce processing steps, and lower costs of depositing super-thin coatings for advanced semiconductor manufacturing. The technology,...

This NSF Engineering Program award of $605,320 to North Carolina State University (NC State) supports the development of a flexible, FMRI-compatible neural probe with multi-modal sensing and modulation capabilities. The novel probe is designed to advance understanding of neural circuit dynamics and enable closed-loop neuromodulation for treating neurological disorders. Key product elements include: Flexible, multi-shank neural probe fabricated using polymeric materials to enable deep brain...

The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a 3-year, $450,000 Project Grant to The Washington University to develop a novel "Plasmon-Enhanced Expansion Fluorospot" (PEEFS) technology. This bioplasmonic imaging method combines fluorescent nanoparticles and expansion microscopy to enable highly sensitive and high-resolution monitoring of cell-secreted proteins at the single-cell level. Key project objectives...

Federal Cooperative Agreement Summary Promedix, Inc. received a $1.14M Cooperative Agreement from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) beginning September 1, 2025, with completion targeted for August 31, 2027. The award supports development of an automated electronic measurement device for quantifying capillary refill time to enhance early diagnosis and treatment of sepsis. The device addresses a critical clinical...

This $274,786 Phase I Small Business Innovation Research (SBIR) award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) will fund the development of a cutting-edge scanning magnetometer microscope by Femtosenselabs, LLC. This new microscope technology will enable high-resolution imaging of novel magnetic materials with unprecedented sensitivity at the nanoscale, supporting the advancement of spintronics and the development of...