Project Grant R43ES038796
- The National Institute of Environmental Health Sciences awarded Materials Nova LIMITED Liability Company $314,745 on September 17, 2025, under the Environmental Health Program (CFDA 93.113) to develop an ultra-sensitive, rapid, point-of-use mercury sensor. Materials Nova will design a portable, user-friendly device that detects low mercury concentrations in water using environment-friendly materials and light-pinpointed enrichment techniques. The sensor will integrate water drawing,...
- The National Institute of Environmental Health Sciences (NIEHS) awarded Xcellassay, Inc. a $306,872 Project Grant under the Environmental Health (CFDA 93.113) federal grant program. The grant funding will support the development and characterization of a hand-held, bioassay-based test strip for rapid, in-field detection of water contamination by endocrine-disrupting chemicals (EDCs). The goal is to create a 1 x 1.5 cm detection strip printed with 20 nuclear receptor sensors that can be...
- The National Institute of Environmental Health Sciences awarded Biota Inc. $306,585 under the Environmental Health grant program (CFDA 93.113) on July 1, 2026, to develop an automated nanoparticle-based sample preparation platform for per- and polyfluoroalkyl substances (PFAS) analysis. The Phase I project establishes feasibility of a fully automated workflow that replaces labor-intensive solid-phase extraction methods in PFAS monitoring. The platform integrates advanced nanoparticle chemistry...
- This $650,000 Project Grant award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) supports the development of engineered microbial sensors for assessing water quality. The primary objective is to create new low-cost sensing systems that can detect chemicals in water throughout the water cycle, including wastewater treatment, drinking water, industrial use, and stormwater discharges. The project employs a convergence research...
- The National Institute of Environmental Health Sciences awarded $306,373 to Luxbiome Inc. on August 24, 2026, under CFDA 93.113 (Environmental Health) to develop microbiome-based solutions for reducing lead exposure in the human body. The project targets the gut microbiome's role in lead metabolism, leveraging preliminary identification of nine bacterial strains that significantly reduce lead tissue accumulation in mice. The approach addresses lead exposure from multiple sources—soil, water,...
- Federal Grant Award Summary Framergy Inc., in collaboration with Texas A&M University, received a $260,993 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective June 1, 2025 through May 31, 2026. The award supports development of a novel at-home detection method for per- and polyfluoroalkyl substances (PFAS) in drinking water. The project leverages metal-organic frameworks (MOFs) and...
- The National Institute of Environmental Health Sciences awarded $305,754 to Innovaprep LLC on September 10, 2025, under the Environmental Health program (CFDA 93.113) to develop a rapid and economical system for per- and polyfluoroalkyl substances (PFAS) sample preparation that lowers method detection limits and enhances high-throughput capabilities. Innovaprep will design and prototype a concentrating pipette system incorporating sorbent-loaded hollow fiber filters for solid-phase extraction...
- The National Institute of Environmental Health Sciences, a division of the Department of Health and Human Services, awarded Uv01 Technologies, Inc. $306,548 under the Environmental Health program (CFDA 93.113) on August 1, 2026, to develop CLYR-VUE, an artificial intelligence and machine learning-powered just-in-time adaptive intervention that addresses indoor air pollution exposure in residential homes. The recipient will develop hardware and software infrastructure incorporating...
- The National Institute of Environmental Health Sciences awarded $612,748 to Luxbiome Inc. on September 12, 2025, under the Environmental Health program (CFDA 93.113) to develop microbiome-based solutions for reducing inorganic arsenic exposure and body burden. The project will optimize human gut bacterial strains and evaluate their efficacy and safety in reducing arsenic uptake, methylation, and efflux through in vitro screening and in vivo modeling. Specific aims include screening bacterial...
- The Centers for Disease Control and Prevention awarded Nanohmics Inc. $1,825,723 on September 30, 2025, under the CDC Investigations and Technical Assistance program (CFDA 93.283) to develop lateral flow-electrochemiluminescent test strips and a portable reader for ultrasensitive detection of foodborne pathogens. Performance occurs in Austin, Texas, with a completion date of September 29, 2027. The project grant supports research and development of diagnostic detection technology intended to...
The National Institute of Environmental Health Sciences awarded Nanohmics Inc. $313,365 on August 1, 2026, under the Environmental Health program (CFDA 93.113) to develop a handheld fluorescent lysosomal yeast biosensor for detecting toxic metal ions and organic pollutants in water. Nanohmics will advance a yeast-based toxicity detection system that exploits the principle that yeast cell vacuoles respond like human lysosomes by acidifying, swelling, and increasing in numbers when exposed to pollutants—changes detectable within 30 to 60 minutes through fluorescent dye staining. The Phase I effort will evaluate saccharomyces yeast response to cadmium (II), chromium (VI), copper (II), lead (II), the pesticides diazinon and malathion, glyphosate, PFAS compounds, and trichloroethylene at low to lethal concentrations. Nanohmics will test yeast suctioned onto filters in microwells using benchtop imaging apparatus and will construct a prototype handheld, battery-operated FLY biosensor—targeting less than $100 in cost and approximately 2 pounds in weight—for tap and well water testing. The prototype will incorporate a photomultiplier tube to enhance fluorescence signal-to-noise ratios and portable pre-concentration columns using hydrophobic matrices and chelators to increase sensitivity and detection speed. Dried yeast exhibits shelf stability across wide temperature ranges, enabling long-term storage in sealed envelopes. This award builds on Nanohmics' previously completed DOD Phase I SBIR, which validated the FLY system for detecting mercury (II), azide, nicotine, and phenol in water. Performance occurs in Austin, Texas. The period of performance runs from August 1, 2026, through July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $313.4k | 7/23/26 |