Project Grant R43ES032357

This $500,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences, under the Biological Sciences federal grant program (CFDA 47.074), will support research to develop an end-to-end continuous manufacturing process for cell therapies using robotics and microfluidic technologies. The Georgia Tech Research Corporation will receive funding to create a more integrated workflow based on microfluidic device-enabled genetic engineering, cell expansion, and...

This $500,000 Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program aims to develop a novel human stem cell-based microfluidic developmental toxicology platform. The University of Michigan will receive funding from September 2022 to August 2024 to conduct technological development of a repeatable, controllable, high-throughput microfluidic system for generating three-dimensional multicellular organoid models for toxicity testing. The platform seeks...

Federal Project Grant Award Summary Vivid Bioinnovations, PBC (operating as Fluid Discovery, Inc.) received a $306,872 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) for the period August 1, 2025 through July 31, 2026. The award supports development of a commercial prototype for an ultrahigh-throughput biocatalyst evolution platform that combines precision nanoliter fluid handling, label-free...

This $256,000 National Science Foundation Project Grant under the NSF Technology, Innovation, and Partnerships program will support the development of a universal connector for high-density microfluidic chip interfaces by Neptune Fluid Flow Systems LLC. The proposed connector aims to advance lab-on-a-chip and other life science platforms by introducing a standardized microfluidic chip interface. This new interface seeks to dramatically increase diagnostic testing speeds for doctors and medical...

Partillion Bioscience Corp. was awarded a $659,037 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences to develop reagent products enabling high-throughput screening and selection of single cells based on secreted bio-products. Under the Biomedical Research and Research Training program (CFDA 93.859), Partillion plans to transition its lab-on-a-particle technology—highlighted as a 2020 SLAS Innovation Award winner—into the first reagent product...

Zaiput Flow Technologies LLC received a $275,000 Project Grant award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop an innovative, continuous crystallization device for pharmaceutical manufacturing. The goal is to improve the purification process of active pharmaceutical ingredients, which is a critical step used in over 90% of pharmaceutical production. The novel device aims to address scalability, cost, and...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded the University of Florida a $616,523 Project Grant on August 8, 2025, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The three-year project, scheduled for completion on July 31, 2028, will develop a generative artificial intelligence (AI)-driven platform for phenotypic drug discovery (PDD) that enables cell morphology-guided, scalable, and...

The National Science Foundation awarded a $450,000 Project Grant to the George Washington University under the Engineering federal grant program (CFDA 47.041) to develop scalable heart-on-a-chip platforms. Over a three-year period from April 2022 through March 2025, the University will create automated systems integrating human heart slice culture components with sensor and actuator arrays. This will enable continuous on-chip multiparametric analysis of human cardiac physiology at the cellular...

The National Institute of General Medical Sciences (NIGMS) awarded a $356,497 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Kinetic River Corp. in Mountain View, CA. This grant, awarded on August 15, 2024, is funding the development of an ultrasensitive flow cytometry system for multiparametric analysis of therapeutic anti-aging extracellular vesicles (EVs). Extracellular vesicles show promise as biomarkers and therapeutics for a range of indications,...

Infinifluidics Inc. received a $256,000 National Science Foundation Project Grant under the Engineering (47.041) federal grant program. The grant supports development of on-demand continuous and sterile manufacturing of injectable drug delivery systems at industrial scale on a portable microfluidic chip from July 1, 2021 to June 30, 2022. The Engineering program seeks to improve quality of life and economic strength through innovative engineering research and education. This award will allow...