Project Grant R43EB033786

The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,609,558 Cooperative Agreement under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative to the University of Chicago. The project, titled "BRAIN CONNECTS: PHOTOEMISSION ELECTRON MICROSCOPY FOR CONNECTOMICS," aims to develop a new type of electron microscope that can significantly reduce the cost of creating comprehensive brain connectivity maps...

This $276,000 National Science Foundation award through the Technology, Innovation, and Partnerships program will support the development of a cognitive dashboard software platform to aid neurosurgical clinical decision-making. Mindtrace Technologies, Inc. will deliver a turn-key software solution that enables neurosurgical teams to map individual patient brain functions, assess and track measures of mental performance throughout care, and integrate with existing medical imaging and data...

This $2,576,654 Project Grant awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support the development of a cloud-based software platform and advanced computational pipelines to harmonize and integrate spatial transcriptomics data for the construction of a spatially resolved brain atlas. Key objectives of the 3-year project include: 1) Creating a cloud-based platform to standardize the analysis and visualization of...

The National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), awarded a $628,559 Cooperative Agreement to The Washington University to develop and disseminate open-source, cloud-based computational tools for optical brain mapping. The project aims to broadly distribute and expand intuitive, validated software resources, including NIRFAST, NeuroDOT, and Network...

The National Science Foundation awarded a $266,000 Project Grant to Columbia University under the NSF Technology, Innovation, and Partnerships federal grant program (CFDA 47.084) to develop a wearable noninvasive brain imaging device using near-infrared light-based time-domain diffuse optical tomography. The device aims to improve clinical outcomes in neurology by enabling measurement of deep brain blood flow, which is difficult to measure with current technologies. The grant will support...

This $679,072 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) aims to establish a platform to accurately recapitulate and perturb cortical development and morphogenesis in vitro. The key objectives are to: 1) Develop bioengineering methods to generate organoids that accurately model the developing human forebrain, including the cortical hem, choroid plexus, and layered cortex; and 2) Establish a high-throughput...

This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $323,978 to the Child Mind Institute Inc., a non-profit organization in New York, to develop novel tools for integrating brain microstructure and functional dynamics in human and non-human primate research. The key products and services to be delivered through this 3-year award include: Extending the existing BrainBuilder tool to...

This federal Project Grant award of $769,352.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program will support the development of an engineered bioprinting platform to study neural migration in brain assembloids - complex 3D models that combine distinct brain organoids to better capture regional interactions critical for neurodevelopment. The award will enable researchers at The Leland Stanford Junior University to: 1) Evaluate...

This federal Project Grant award of $830,409.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports the development of novel software and computational techniques that integrate real-time electric-field mapping and source-space electroencephalogram (EEG) analysis to improve the accuracy of transcranial magnetic stimulation (TMS) targeting and dosimetry for individualized treatment of brain diseases. The key products and...

This $524,243 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will fund the development of a new portable TMS-EEG device called PRESENCE. The device combines a novel consciousness detection algorithm, PRESENCE-IP1.0, with a portable data acquisition system to enable bedside assessment of consciousness in patients with disorders of...