Project Grant R43EB031671
- This SBIR Phase I Project Grant, awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, is developing a novel minimally invasive procedure for deploying an implantable spinal cord stimulation (SCS) lead using a shape memory polymer (SMP). The $304,259 project, which runs from October 1, 2025 to June 30, 2026, aims to create an 8-channel SMP-based paddle lead that can be molded into a compact configuration for minimally...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), provides $3,473,616 to the University of Connecticut to develop a novel implantable neuromodulation system called "SmartStim" to treat chronic pain. The goal is to create a combined device and drug treatment that can selectively block sensitized nociceptive (pain-sensing) nerve fibers, especially C-fibers, to reverse the underlying neural...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $3,565,780 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop a groundbreaking high-frequency trans-spinal magnetic stimulation (HF-TSMS) system for the non-invasive treatment of neuropathic pain. The funded project aims to create an HF-TSMS tool that can target neural pathways involved in...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,976 to Ecate LLC aims to develop a novel intraspinal stimulator system to restore sensation and volitional motor control in spinal cord injury patients. The project will fabricate nanopatterned stimulating electrodes coupled with custom CMOS chips to deliver spatially selective electrical stimulation to the spinal cord. This closed-loop neural interface system is intended...
- This $165,000 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) supports research and development of magnetic spinal cord stimulation (MSCS) technologies. The project aims to model and assess the safety of MSCS, an emerging neuromodulation technique that uses external coils to induce electric fields in the spinal cord. Unlike...
- This Project Grant award, valued at $206,132 and provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a wireless, battery-free bioelectronic implant for closed-loop neuromodulation to treat detrusor sphincter dyssynergia (DSD) in individuals with spinal cord injury. The University of Houston System, the awardee, will fabricate and...
- The National Science Foundation Division of Industrial Innovation awarded Spinex Inc. a $255,568 Project Grant under the Engineering (47.041) federal grant program. The grant funded the development of a transcutaneous electrical spinal cord neuromodulator for home use from September 1, 2021 to February 28, 2022. As part of its mission to foster innovation and excellence in engineering, the Engineering program supported Spinex Inc.'s work to advance technologies for non-invasive spinal cord...
- The Spinex Inc. was awarded a $4,719,091 Project Grant from the National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases to develop and clinically validate a transcutaneous electrical spinal cord neuromodulation (TESCON) device to mitigate symptoms of neurogenic bladder resulting from spinal cord injury. The award, made under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support Spinex in building a commercial...
- This $2,668,301 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant funds the development of an implantable, biodegradable drug delivery device for localized, long-duration administration of non-opioid pain medications after surgery. The University of Connecticut will synthesize protein-based film materials conjugated with...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), will support research to generate evidence-based knowledge about the neural mechanisms underlying the spatiotemporal control of transcutaneous spinal cord stimulation (TSCS) for restoring motor function in individuals with spinal cord injury (SCI). The $570,718 award, with a project...
Teliatry Inc. received a $768,138 project grant award from the National Institutes of Health's National Institute of Biomedical Imaging and Bioengineering to develop a minimally invasive, single incision, rechargeable spinal cord stimulation system for chronic pain management. The grant was awarded under the Discovery and Applied Research for Technological Innovations to Improve Human Health program. Through this award, Teliatry will engineer the world's smallest (0.75cc), most cost-effective spinal cord stimulator system that eliminates the need for tunneling wires and creating an implantable pulse generator pocket through surgery. The company's novel shape memory polymer lead can be inserted percutaneously and "unrolls" in the epidural space to function as a paddle. Integrated high surface area, low polarization titanium nitride electrodes and a miniature solid state battery architecture are designed to significantly reduce energy needs and battery replacement surgeries over the lifetime of the implant. If successful, this technology could help mainstream spinal cord stimulation therapy for chronic pain.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 9/22/22 | ||
| Not listed | $0 | 9/22/22 | ||
| Not listed | $0 | 5/26/21 | ||
| Not listed | $0 | 5/26/21 | ||
| Not listed | $256.0k | 3/26/21 |