Project Grant R43DK143762
- This federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $306,867 award to Dupage Medical Technology Inc. supports the development of a new drug to treat ischemia-reperfusion injury associated with kidney transplantation. The project aims to develop a therapy that can reduce inflammation and thrombosis without causing excessive...
- This federal Project Grant award of $178,026 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, awarded to Inphasol Inc. in College Station, TX, aims to develop bacteriophages to target and reduce Desulfovibrio spp. bacteria in the gut microbiome. This is expected to reduce the production of hydrogen sulfide, which can contribute to malodorous...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a component of the National Institutes of Health, awarded a $292,116 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Renovate Biosciences Inc. The grant aims to generate human livers from donor patient-specific cells using pigs as a "bio-incubator" for xenotransplantation, with the long-term goal of producing immune-compatible solid organs for...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $423,017 to investigate the use of Lumbricus terrestris erythrocruorin (LTEC), a novel red blood cell substitute, for extending the duration of normothermic ex vivo kidney perfusion (NEVKP). The goal is to develop LTEC as an oxygen carrier to improve the viability and function of kidneys maintained outside the...
- This Project Grant award of $348,150.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports the development of Avantamine, a novel antimicrobial chloramine formulation, by Halomine Inc. (doing business as Avantguard). The goal is to optimize Avantamine's efficacy against bacteria found in diabetic foot ulcers to improve treatment and healing outcomes. The project involves evaluating...
- This federal Project Grant award of $842,633.00, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is focused on developing an optimal prehabilitation program for kidney transplant candidates on hemodialysis. The grant aims to elicit expert opinion to identify kidney transplant-specific prehabilitation components and strategies to enhance enrollment and adherence...
- This $186,476 Project Grant from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research to investigate the contribution of hydrogen sulfide to the pathophysiology of Duchenne muscular dystrophy (DMD). The grant will fund experiments to characterize the effects of chronic, systemic hydrogen sulfide supplementation on DMD pathophysiology in vivo, as well as the effects of low hydrogen sulfide levels on the oxidation and contractile function...
- This Project Grant award of $314,279 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports the development and evaluation of an innovative dialysis cannulation needle. The proposed product aims to reduce accidental needle infiltration injuries and improve the safety and efficacy of home and in-center renal dialysis therapy. The award was made to Minnesota Healthsolutions Corporation, a...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through its Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $350,000 Project Grant to Katharos, Inc. on Jun 20, 2025. The grant supports the development of a novel extracorporeal technology, the "Phosfilter" device, which aims to enhance phosphate removal from the blood of hemodialysis patients and reduce the incidence of high phosphate-associated morbidity and...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $175,964 Project Grant to Hepatx Corporation in Palo Alto, CA on May 13, 2025. The grant aims to develop a proteomic assay, or blood test, to monitor the success of cell transplantation therapies, such as hepatocyte (liver cell) transplantation, for treating chronic diseases. This novel assay would enable the...
This $248,492 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) supports the development of a "Hydrogen Sulfide Delivery Technology for Organ Preservation Therapy" by Exhalix, LLC, a for-profit company based in Albuquerque, New Mexico. The project aims to address the significant shortage of viable donor kidneys for transplantation by developing a technology to reduce ischemia-reperfusion injury (IRI) and improve delayed graft function through the use of hydrogen sulfide (H2S). The 2-year project, running from September 2025 to August 2027, will further Exhalix's research into leveraging H2S as a cytoprotective agent to enhance organ preservation and transplant outcomes.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $248.5k | 9/8/25 |