This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $310,170 to Cathpro Technologies, LLC to develop an innovative luminal insert for vascular catheters. The goal is to create a product that combines anti-infective and anti-thrombotic technologies to effectively reduce intraluminal infections and thrombotic occlusions in catheters. The funding will support feasibility studies to optimize...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $499,890 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to Pavaj Vascular Corporation in Rochester, MN. The funding will support the development and evaluation of a novel therapy to prevent venous stenosis and neointimal hyperplasia in arteriovenous fistulas used for hemodialysis in patients with end-stage kidney disease. The project aims to 1) assess the stability...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is funding the development of an implantable device to improve vascular access and safety for hemodialysis patients. The $324,836 Phase I SBIR grant to Flowpoint Medical Inc. will be used to refine the manufacturability and operational parameters of a 3D-printed titanium device that guides the...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $299,999 Project Grant (CFDA 93.847) to Hibar Microsciences, LLC to develop a prototype for CLEAR, a novel hemodialysis cartridge designed to improve the clearance of protein-bound uremic toxins (PBUTs) from the blood of patients with end-stage renal disease. The key objectives are to: 1) Develop a method for immobilizing lipocalin proteins onto dialysis membrane matrices to enhance PBUT removal; 2) Create and...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $518,661 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to Vanderbilt University Medical Center (VUMC) to conduct research on improving dialysis treatment for the 548,000 Americans who rely on it for kidney failure. The project aims to evaluate novel dialyzer designs that can better remove protein-bound uremic toxins and reduce platelet activation, which are key...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under CFDA Program 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research, provides $1,955,984 to Biodevek Inc. to develop GastroShield, a sprayable biocompatible adhesive biomaterial for endoscopic management of gastrointestinal (GI) lesions and prevention of GI bleeding. The project aims to achieve critical pre-clinical study milestones, including scaling up manufacturing,...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded $809,976 to Cathbuddy Inc. under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to support the development of a 6-inch version of the company's Aurie Reusable Catheter System. This novel urinary catheterization system incorporates a personal portable washer-disinfecting carrying case that allows for safe reuse of no-touch catheters, reducing infection risks, per-use costs,...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $256,501 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Silicon Kidney LLC. The funding supports the development of an Intracorporeal Hemodialysis System (IHEMO) to address mortality disparities among rural and remote end-stage kidney disease patients. The key products and services to be delivered include: Identifying a zeolite material with...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides USD 658,800 to The Research Foundation For The State University Of New York to conduct research on the urothelial glycosaminoglycan (GAG) layer and its role in catheter-associated urinary tract infections (CAUTIs). The key objectives of the research project are to: Comprehensively examine...
This federal Project Grant award, with an ID of K01DK140529, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under their Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $156,703 award, effective from August 1, 2024 to May 31, 2029, supports research to diagnose, treat, and monitor polymicrobial infections in diabetic wounds. The project aims to leverage a bacterial metabolite, glutamate 1-semialdehyde (GSA),...