Project Grant R43DK120242

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is supporting the development of novel minimally invasive catheter-based devices for endovascular filtration. The goal is to remove chemotherapy drugs from the blood in order to reduce systemic toxicity during locoregional infusion therapy. The $670,440 award, granted on May 21,...

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through its Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $350,000 Project Grant to Katharos, Inc. on Jun 20, 2025. The grant supports the development of a novel extracorporeal technology, the "Phosfilter" device, which aims to enhance phosphate removal from the blood of hemodialysis patients and reduce the incidence of high phosphate-associated morbidity and...

The National Science Foundation (NSF) has awarded a $1,000,000 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to Aidar Health, Inc.'s Rapid Advantage Division. The purpose of this 2-year award is to develop a comprehensive remote health management system for patients with chronic kidney disease. Key deliverables include a medical device, digital tools with advanced analytics capabilities, and a novel patient engagement feature using...

This $255,982 National Science Foundation project grant supports the development of sustainable, cost-effective viral clearance membranes by Filtravate, Inc. to enable efficient monoclonal antibody processing. The NSF Technology, Innovation, and Partnerships program seeks technologies leading to breakthrough solutions for national challenges. Specifically, Filtravate will develop a virus filtration membrane using a synthesis process that is more sustainable and affordable than conventional...

This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) provides $275,000 to Carrtech Corp, a woman-owned small business manufacturer, to develop an integrated, single-needle filter system to remove glass shards from injectable fluids. The project aims to create a novel, disposable, inline mechanical filter that addresses the current multi-step process healthcare providers must use to filter glass ampoules prior to injection,...

This Project Grant award from the National Heart, Lung, and Blood Institute's Cardiovascular Diseases Research program (CFDA 93.837) totaling $715,110.00 aims to develop and optimize a novel "nano-RBC" blood substitute prototype. The key products and services to be delivered include: The project will use computational studies, synthetic and biological experiments to design a "smart" oxygen-delivery biomaterial with physiological oxygen binding/dissociation properties,...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $423,017 to investigate the use of Lumbricus terrestris erythrocruorin (LTEC), a novel red blood cell substitute, for extending the duration of normothermic ex vivo kidney perfusion (NEVKP). The goal is to develop LTEC as an oxygen carrier to improve the viability and function of kidneys maintained outside the...

This $550,000 Project Grant awarded by the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) supports the development of a remote monitoring system to reduce peritoneal dialysis (PD) infections. The project aims to create a medical device that can provide real-time, continuous monitoring of biomarkers in dialysate fluid to enable earlier detection and treatment of PD-associated infections. The key products and services to be delivered include: (1)...

This $256,000 National Science Foundation project grant supports the development of an automated chest tube to prevent clotting. Circulatech LLC will design and prototype a novel chest tube that proactively manages fluid flow within the catheter lumen to flush and drain the tube, reducing blood clot formation. Through a process called "dilutional coagulopathy," the tube will use sterile saline or anticoagulants to reduce thrombosis in the drainage space rather than relying on...

The National Center for Advancing Translational Sciences (NCATS) awarded a $275,000 Project Grant (CFDA 93.350) to Nectagen Inc. to develop bioprocess-compatible, second-generation nanoclamp affinity resins for the efficient purification of plasma-based therapeutic proteins. The goal is to identify panels of nanoclamps to 5 industrially relevant plasma-based therapeutics, select lead candidates, and optimize the resins for maximum recovery and purity from plasma samples. This project aims to...