Project Grant R43DK117801

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK - CFDA 93.847) to Biomedinnovations, Inc. (BMI Organbank) will fund the development of a platform for extended kidney preservation via subnormothermic perfusion. The $3,740,270 award, effective September 20, 2024 through June 30, 2026, aims to optimize BMI's perfusion device and perfusate, evaluate the impact of warm ischemic injury and preservation duration, and compare the function of...

This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $1,800,000 to Missouri University of Science & Technology to develop an artificial intelligence decision support system for kidney transplant healthcare. The goal is to reduce kidney discard rates by at least 10% by embedding preferences and fairness considerations into AI models used to match donor kidneys with transplant centers. Two subawards totaling $XXX,XXX are provided to Saint...

The National Institutes of Health Office of the Director awarded the University of Southern California a $2.9 million project grant under the Trans-NIH Research Support program (CFDA 93.310) to develop a synthetic kidney as a revolutionary solution to the shortage of kidneys available for transplantation. The three-year project will generate a transplantable synthetic kidney using stem cell and bioengineering technologies, then evaluate its growth, differentiation, vascularization and functional...

The University of Louisville received a $159,701 project grant award from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation to support research titled "COLLABORATIVE RESEARCH: SCH: OPTIMAL DESENSITIZATION PROTOCOL IN SUPPORT OF A KIDNEY PAIRED DONATION (KPD) SYSTEM." The award period is from October 1, 2021 to September 30, 2025. The research aims to develop an optimal desensitization protocol to support a kidney paired donation system. This...

The National Science Foundation awarded a $167,704 Project Grant to the University of Maryland, College Park under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). The grant supports collaborative research to develop an optimal desensitization protocol to facilitate a kidney paired donation system. The research aims to advance the use of desensitization therapy to expand compatible donor options for kidney transplant candidates. Over a four-year period...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $351,377 to Mayo Clinic to develop artificial intelligence-based methods to characterize kidney macrostructure from pre- and post-nephrectomy computed tomography (CT) images. The overarching goal is to evaluate automated imaging biomarkers as prognostic tools for predicting...

This Project Grant award of $306,873 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) aims to develop an AI-driven automated system for accurately generating Banff lesion scores from kidney biopsy slides. The project, titled "BANFF-AID: BANFF Automated Nephrology Feature Framework - Artificial Intelligence Diagnosis", will create custom AI models to extract...

The federal Project Grant award R01DK140129, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to optimize the allocation of kidneys from deceased African American donors with APOL1 high-risk genotypes. The primary goal is to identify clinically actionable approaches to determine which of these kidneys are truly "high risk" for...

This Project Grant award, ID R01DK138067, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $1,470,094 award supports the development of an artificial intelligence-powered tool to improve preimplantation kidney transplant biopsy interpretation and reduce inappropriate discard of potentially viable kidneys. Key objectives include constructing a comprehensive...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) will support a 5-year, $193,652 research project to assess the impact of cognitive biases on patient and provider willingness to accept imperfect kidneys for transplantation. The project aims to characterize status quo bias that may cause patients to underestimate the risks of continued dialysis relative to transplant,...