Project Grant R43DK104564

This Cooperative Agreement award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,250,000 in funding to Biodevek Inc., a Boston-based small business, to advance the development of a novel hydrogel delivery system for managing gastrointestinal (GI) lesions and bleeding. The project aims to create the first sprayable hemostatic hydrogel solution for endoscopic procedures, with the potential to improve outcomes, reduce...

This $250,000 National Science Foundation project grant supports the development of a microneedle-mediated adaptive phototherapy wound dressing by the University of South Florida from October 1, 2022 to November 30, 2024. The dressing integrates self-diagnosis and treatment tailored to wound conditions without external electronics or medical professionals. Microstructured microneedles act as optical waveguides to deliver localized blue or red light therapy at wound sites, changing wavelength...

This $100,000 National Science Foundation Technology, Innovation, and Partnerships grant funds the development of tunable porosity aerogel for wound care dressings at The University of Akron from July 1, 2022 to June 30, 2023. The project aims to create a novel bio-based aerogel dressing that could help heal patients with chronic wounds faster by requiring fewer dressing changes. Aerogels' high porosity, surface area and moisture balance properties may create an incubator-like wound healing...

The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), awarded a $350,000 Project Grant to Karios Technologies LLC to develop TissueShield, a novel single-use, ready-to-use, sterile, dual-chamber, dual-syringe sprayable hydrogel for preventing post-surgical cardiac adhesions. TissueShield is a 3-component polymer system that can be easily sprayed directly onto the heart, forming a robust anti-adhesion layer within seconds. The...

This $234,000 Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports a two-year clinical research initiative (August 1, 2025 – July 31, 2027) led by the University of Michigan. The project will conduct a 100-patient clinical trial to evaluate the prevalence and treatment of rectal evacuation disorders in patients with hemorrhoidal bleeding—a...

Federal Project Grant Award Summary Averto Medical Inc. received a $1.19M Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), dated September 19, 2025, with completion targeted for August 31, 2027. The award supports a safety and efficacy clinical trial of the COLOSEAL Intraluminal Colonic Exclusion (ICD) System, a minimally invasive medical device...

This National Science Foundation (NSF) Engineering Research Initiation (ERI) Project Grant, awarded by the NSF Division of Chemical, Bioengineering, Environmental, and Transport Systems, aims to develop a new type of bioadhesive using hydrophilic polydopamine (HPDA) to improve healing of inner meniscus tears. The project will synthesize and characterize HPDA, then incorporate it into hydrogel-based bioadhesives to be tested in vitro. The specific objectives are to understand the adhesion...

The National Science Foundation (NSF) awarded a $275,000 Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Auxilium Health, Inc. for the development and validation of an aerogel-based biomaterial wound dressing. The proposed innovation aims to create a multi-layer wound dressing platform with integrated fluid management, biofilm prevention, and rapid infection detection capabilities to improve the management of acute wounds, chronic wounds, surgical...

This $1,017,602 National Science Foundation project grant supports research at North Carolina State University to develop microphysiological models for evaluating the role of age-dependent fibrinogen sialylation in wound healing. The three-year award under the NSF Engineering program (CFDA 47.041) will fund the creation of innovative tissue engineering techniques and microfluidic systems to study interactions between platelets and fibroblasts during wound healing. Researchers aim to better...

Federal Grant Award Summary Fesariustherapeutics Inc. received a $349,892 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025 through August 31, 2026. The company is developing DermisphereShield, an antimicrobial dermal regeneration template designed to address wound healing challenges in contaminated or resource-constrained environments. This product targets...